WORLD JOURNAL OF PLASTIC SURGERY

en Comparison the Effect of Conventional and Nanofat Injection Methods on Nasolabial Fold Lipofilling: A Case- Control Study تخصصي Special مقالات اصيل Original Article ABSTRACT Background: Nasolabial folds are a common sign of aging, accompanied by various manifestations such as skin and tissue loosening, wrinkles, lip corner drooping, mandibular angle loss, platysmal bands, and skin pigmentation changes. Limited research has explored Nanofat injection methods. this study was done with the aim of comparing the effect of fat injection by two methods, conventional and Nanofat, in nasolabial folds. Method: The study conducted in 2020-2021 at the skin clinic in Ilam, western Iran was a case-control study. Participants were divided into two groups, and lipofilling procedures were performed using conventional and nanofat methods with autologous fat. Data collection utilized a researcher-made questionnaire and radiographic results. Follow-up visits occurred on the 30th, 90th, and 180th days to assess complications and recovery rates. After 6 months, participant's photographs were taken and compared with pre-intervention photographs using the GIAS criteria. Data analysis was conducted using SPSS22 version software. Results: The average age of the participants was 37.80±8.30 yr. The treatment response in the conventional fat injection group was significantly better than the nanofat group (P<0.05). Both groups were satisfied with the treatment methods, but high satisfaction was reported in the conventional group, but there was no statistically significant difference between the groups. Conclusion: Both methods of improving wrinkles were effective, but the improvement and response to treatment in the conventional method was better than the Nanofat method, and its effect was felt by the participants for an average period of 3 months.   Fat injection, Conventional, Nanofat, Wrinkles, Nasolabial fold, Lipofilling 24 31 http://wjps.ir/browse.php?a_code=A-10-843-6&slc_lang=en&sid=1 Mina Mamizadeh 100319475328460015279 100319475328460015279 No Department of Dermatology, School of Medicine, Emam Khomeini Hospital, Ilam University of Medical sciences, Ilam, Iran Samaneh Tahmasebi Ghorabi 100319475328460015280 100319475328460015280 No USERN Office, Lorestan University of Medical Sciences, Khorramabad, Iran Zahra Mansourinia 100319475328460015281 100319475328460015281 No Ilam University of Medical Sciences, Ilam, Iran Fariba Shadfar 100319475328460015282 100319475328460015282 No Department of Dermatology, School of Medicine, Emam Khomeini Hospital, Ilam University of Medical sciences, Ilam, Iran Arian Karimi Rouzbahani ariankarimi1998@gmail.com 100319475328460015283 100319475328460015283 Yes USERN Office, Lorestan University of Medical Sciences, Khorramabad, Iran