en تخصصي Special مقالات اصيل Original Article <span style="font-size:11pt"><span style="line-height:150%"><span calibri="" style="font-family:"><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Pressure injury/ulcer is localized damage to the skin and/or underlying tissues primarily caused by prolonged unrelieved pressure, particularly in patients with limited mobility. The increasing incidence of pressure injuries as a result of </span></span></span><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">aging population and growing number of nursing home residents along with the posing socio-economic burden highlights the importance of increasing our understanding of this global problem, and the available preventive and therapeutic strategies. Surgical intervention using flap reconstruction is the mainstay therapy for management of pressure injuries with advanced stages. We present a comprehensive review on various types, indications, advantages and limitations of flaps used in reconstruction of advanced-stage pressure injuries.</span></span></span></span></span></span><br> &nbsp; Pressure injury, Flap reconstruction, Local flaps, Regional flaps, Perforator flaps, Free flaps 3 9 http://wjps.ir/browse.php?a_code=A-10-954-2&slc_lang=en&sid=1 Shima Bani Assad 100319475328460016466 100319475328460016466 No Department of Anesthesiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Peyman Sadri 100319475328460016467 100319475328460016467 Yes Department of General Surgery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran