en عمومى General مروری Review Article <div><span style="font-size: 13px;">BACKGROUND</span></div> <div><span style="font-size: 13px;">Patients with spinal cord injury (SCI) tend to develop pressure ulcers (PrUs) because of prolonged immobility. This study assessed the efficacy of vacuum assisted closure for healing of PrUs in individuals with SCI.</span></div> <div><span style="font-size: 13px;">METHODS</span></div> <div><span style="font-size: 13px;">In a systematic review, CINAHL, PubMed, Cochrane Clinical Trials, DARE, MEDLINE, Scopus, Embase, Science Direct, PsycInfo and Spinal Cord Journal were searched in March 2019. The search combined related terms for pressure ulcer, spinal cord injury, and vacuum assisted closure. Each database was searched from its inception with no restrictions on year of publication.&nbsp;</span></div> <div><span style="font-size: 13px;">RESULTS</span></div> <div><span style="font-size: 13px;">The search yielded 7 studies for inclusion in a qualitative analysis. The studies included a variety of methodologies, specifically 2 randomized controlled trials, 2 assessor-blinded crossover and retrospective cohort study, 1 prospective non-randomized trial, 1 randomized case study and 1 case report. The meta-analysis was unsuccessful. Only descriptive results mean&plusmn;SD were reported as well as time to heal and time to discharge after admission.&nbsp;</span></div> <div><span style="font-size: 13px;">CONCLUSION</span></div> <div><span style="font-size: 13px;">The studies that we included in our qualitative synthesis showed that vacuum assisted closure promoted the healing of PrUs in individuals with SCI.</span></div> Pressure ulcer, Spinal cord injury, Vacuum assisted closure, Intermittent negative pressure 279 284 http://wjps.ir/browse.php?a_code=A-10-508-1&slc_lang=en&sid=1 Avraam Ploumis aploumis@cc.uoi.gr 10031947532846007276 10031947532846007276 Yes University of Ioannina, Department of Physical Medicine and Rehabilitation George Mpourazanis georgempourazanis@gmail.com 10031947532846007277 10031947532846007277 No University of Ioannina, Department of Medicine Christina Martzivanou christina.martzi@yahoo.de 10031947532846007278 10031947532846007278 No University of Ioannina, Department of Medicine Pantelis Mpourazanis pantbpourazanis@gmail.com 10031947532846007279 10031947532846007279 No Univeristy of Ioannina, Department of Chemistry Areti Theodorou areti.theodor@gmail.com 10031947532846007280 10031947532846007280 No University of Ioannina, Department of Physical Medicine and Rehabilitation