Volume 15, Issue 1 (2026)
WJPS 2026, 15(1): 71-79 |
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Ashkan Golabkesh Afshar1 
, Sara Pilehvar1 , Navid Kazemian1 , Majid Hosseini Abrishami1 , Shayan Yousefi2 , Sahand Samieirad *3
, Sara Pilehvar1 , Navid Kazemian1 , Majid Hosseini Abrishami1 , Shayan Yousefi2 , Sahand Samieirad *3
1- 1. Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
2- 2. Student Research Committee, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
3- 1. Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran ,Samieerads@mums.ac.ir
2- 2. Student Research Committee, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
3- 1. Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran ,
Abstract: (1323 Views)
Ameloblastoma, a benign but locally aggressive neoplasm, frequently requires substantial surgical resection to avert recurrence, potentially leading to considerable mandibular abnormalities. This case report examines a 31-year-old female patient diagnosed with a multilocular ameloblastoma, originally treated with marginal excision and subsequent reconstruction utilizing a conventional plate. The patient was admitted to Velayat Hospital in Mashhad, Iran, in 2024 and received the necessary medical treatment there. Complications, including as plate exposure and jaw deviation, arose a year later, requiring further operation. The patient underwent a second operation to remove the defective plate and to insert a bespoke digital reconstructive plate. The customized plate was engineered to conform to her distinct anatomical configuration, guaranteeing accurate alignment and enhanced biomechanical efficacy. The post-operative recovery was positive, with restored mandibular alignment, enhanced function, and no recurrence of problems. This case demonstrates the effectiveness of tailored digital reconstruction plates in managing intricate mandibular abnormalities, yielding improved results in functionality, aesthetics, and patient comfort.
Keywords: Ameloblastoma, Mandibular Reconstruction, Reconstruction Plate, Customized Plate, Case Report
References
1. Kalmegh PP, Hande AH, Gawande MN, Patil SK, Sonone AM. Unicystic Ameloblastoma (UA): A Case Series. Cureus 2022 Nov;14(11):e31039. [DOI:10.7759/cureus.31039]
2. Gupta N, Saxena S, Rathod VC, Aggarwal P. Unicystic ameloblastoma of the mandible. J Oral Maxillofac Pathol 2011 May;15(2):228-31. [DOI:10.4103/0973-029X.84511]
3. Eversole LR, Leider AS, Hansen LS. Ameloblastoma with pronounced desmoplasia. J Oral Maxillofac Surg 1984 Nov;42(11):735-40. [DOI:10.1016/0278-2391(84)90423-3]
4. Arotiba GT, Ladeinde AL, Arotiba JT, Ajike SO, Ugboko VI, Ajayi OF. Ameloblastoma in Nigerian children and adolescents: a review of 79 cases. J Oral Maxillofac Surg 2005 Jun;63(6):747-51. [DOI:10.1016/j.joms.2004.04.037]
5. Fregnani ER, da Cruz Perez DE, de Almeida OP, Kowalski LP, Soares FA, de Abreu Alves F. Clinicopathological study and treatment outcomes of 121 cases of ameloblastoma. Int J Oral Maxillofac Surg 2010 Feb;39(2):145-9. [DOI:10.1016/j.ijom.2009.11.022]
6. Ueno S, Nakamura S, Mushimoto K, Shirasu R. A clinicopathologic study of ameloblastoma. J Oral Maxillofac Surg 1986 May;44(5):361-5. [DOI:10.1016/S0278-2391(86)80031-3]
7. Dhanuthai K, Chantarangsu S, Rojanawatsirivej S, et al. Ameloblastoma: a multicentric study. Oral Surg Oral Med Oral Pathol Oral Radiol 2012 Jun;113(6):782-8. [DOI:10.1016/j.oooo.2012.01.011]
8. 8 McIvor J. The radiological features of ameloblastoma. Clin Radiol 1974 Apr;25(2):237-42. [DOI:10.1016/S0009-9260(74)80060-7]
9. Rapidis AD, Andressakis DD, Stavrianos SD, et al. Ameloblastoma of the jaws: clinico-pathological review of 11 patients. Eur J Surg Oncol 2004 Nov;30(9):998-1002. [DOI:10.1016/S0748-7983(04)00198-2]
10. Almeida Rde A, Andrade ES, Barbalho JC, Vajgel A, Vasconcelos BC. Recurrence rate following treatment for primary multicystic ameloblastoma: systematic review and meta-analysis. Int J Oral Maxillofac Surg 2016 Mar;45(3):359-67. [DOI:10.1016/j.ijom.2015.12.016]
11. Effiom OA, Ogundana OM, Akinshipo AO, Akintoye SO. Ameloblastoma: current etiopathological concepts and management. Oral Dis 2018 Apr;24(3):307-16. [DOI:10.1111/odi.12646]
12. Ghandhi D, Ayoub AF, Pogrel MA, MacDonald G, Brocklebank LM, Moos KF. Ameloblastoma: a surgeon's dilemma. J Oral Maxillofac Surg 2006 Jul;64(7):1010-4. [DOI:10.1016/j.joms.2006.03.022]
13. Gardner DG, Pecak AM. The treatment of ameloblastoma based on pathologic and anatomic principles. Cancer 1980 Dec 1;46(11):2514-9.
https://doi.org/10.1002/1097-0142(19801201)46:11<2514::AID-CNCR2820461133>3.0.CO;2-9 [DOI:10.1002/1097-0142(19801201)46:113.0.CO;2-9]
14. Heikinheimo K, Kurppa KJ, Elenius K. Novel targets for the treatment of ameloblastoma. J Dent Res 2015 Feb;94(2):237-40. [DOI:10.1177/0022034514560373]
15. Kudo K, Shoji M, Yokota M, Fujioka Y. Evaluation of mandibular reconstruction techniques following resection of malignant tumors in the oral region. J Oral Maxillofac Surg 1992 Jan;50(1):14-21. [DOI:10.1016/0278-2391(92)90186-4]
16. Schöning H, Emshoff R. Primary temporary AO plate reconstruction of the mandible. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998 Dec;86(6):667-72. [DOI:10.1016/S1079-2104(98)90201-3]
17. Tayapongsak P, Morales MJ, Marx RE. Preresection application of reconstruction plates for temporary mandibular reconstruction. J Oral Maxillofac Surg 1992 Mar;50(3):307-9. [DOI:10.1016/0278-2391(92)90335-W]
18. Chow JM, Hill JH. Primary mandibular reconstruction using the AO reconstruction plate. Laryngoscope 1986 Jul;96(7):768-73. [DOI:10.1288/00005537-198607000-00013]
19. Wilde F, Hanken H, Probst F, Schramm A, Heiland M, Cornelius CP. Multicenter study on the use of patient-specific CAD/CAM reconstruction plates for mandibular reconstruction. Int J Comput Assist Radiol Surg 2015 Dec;10(12):2035-51. [DOI:10.1007/s11548-015-1193-2]
20. Sieira Gil R, Roig AM, Obispo CA, Morla A, Pagès CM, Perez JL. Surgical planning and microvascular reconstruction of the mandible with a fibular flap using computer-aided design, rapid prototype modelling, and precontoured titanium reconstruction plates: a prospective study. Br J Oral Maxillofac Surg 2015 Jan;53(1):49-53. [DOI:10.1016/j.bjoms.2014.09.015]
21. Azuma M, Yanagawa T, Ishibashi-Kanno N, et al. Mandibular reconstruction using plates prebent to fit rapid prototyping 3-dimensional printing models ameliorates contour deformity. Head Face Med 2014 Oct 23;10:45. [DOI:10.1186/1746-160X-10-45]
22. Liang Y, Jiang C, Wu L, Wang W, Liu Y, Jian X. Application of Combined Osteotomy and Reconstruction Pre-Bent Plate Position (CORPPP) Technology to Assist in the Precise Reconstruction of Segmental Mandibular Defects. J Oral Maxillofac Surg 2017 Sep;75(9):2026.e1-.e10. [DOI:10.1016/j.joms.2017.04.046]
23. Ueyama Y, Naitoh R, Yamagata A, Matsumura T. Analysis of reconstruction of mandibular defects using single stainless steel A-O reconstruction plates. J Oral Maxillofac Surg 1996 Jul;54(7):858-62; discussion 62-3. [DOI:10.1016/S0278-2391(96)90536-4]
24. Yi Z, Jian-Guo Z, Guang-Yan Y, Ling L, Fu-Yun Z, Guo-Cheng Z. Reconstruction plates to bridge mandibular defects: a clinical and experimental investigation in biomechanical aspects. Int J Oral Maxillofac Surg 1999 Dec;28(6):445-50. [DOI:10.1034/j.1399-0020.1999.280608.x]
25. Shibahara T, Noma H, Furuya Y, Takaki R. Fracture of mandibular reconstruction plates used after tumor resection. J Oral Maxillofac Surg 2002 Feb;60(2):182-5. [DOI:10.1053/joms.2002.29817]
26. Almansoori AA, Choung HW, Kim B, Park JY, Kim SM, Lee JH. Fracture of Standard Titanium Mandibular Reconstruction Plates and Preliminary Study of Three-Dimensional Printed Reconstruction Plates. J Oral Maxillofac Surg 2020 Jan;78(1):153-66. [DOI:10.1016/j.joms.2019.07.016]
27. Narra N, Valášek J, Hannula M, et al. Finite element analysis of customized reconstruction plates for mandibular continuity defect therapy. J Biomech 2014 Jan 3;47(1):264-8. [DOI:10.1016/j.jbiomech.2013.11.016]
28. Moiduddin K, Anwar S, Ahmed N, Ashfaq M, Al-Ahmari A. Computer Assisted Design and Analysis of Customized Porous Plate for Mandibular Reconstruction. IRBM 2017 2017/04/01/;38(2):78-89. [DOI:10.1016/j.irbm.2017.01.003]
29. Mazzoni S, Marchetti C, Sgarzani R, Cipriani R, Scotti R, Ciocca L. Prosthetically guided maxillofacial surgery: evaluation of the accuracy of a surgical guide and custom-made bone plate in oncology patients after mandibular reconstruction. Plast Reconstr Surg 2013 Jun;131(6):1376-85. [DOI:10.1097/PRS.0b013e31828bd6b0]
30. Kokosis G, Davidson EH, Pedreira R, Macmillan A, Dorafshar AH. The Use of Computer-Aided Design and Manufacturing in Acute Mandibular Trauma Reconstruction. J Oral Maxillofac Surg 2018 May;76(5):1036-43. [DOI:10.1016/j.joms.2017.12.008]
31. Yang WF, Zhang CY, Choi WS, et al. A novel 'surgeon-dominated' approach to the design of 3D-printed patient-specific surgical plates in mandibular reconstruction: a proof-of-concept study. Int J Oral Maxillofac Surg 2020 Jan;49(1):13-21. [DOI:10.1016/j.ijom.2019.05.005]
32. McClary AC, West RB, McClary AC, et al. Ameloblastoma: a clinical review and trends in management. Eur Arch Otorhinolaryngol 2016 Jul;273(7):1649-61. [DOI:10.1007/s00405-015-3631-8]
33. Saraiya HA. Wide Excision with Immediate Reconstruction of the Mandible Using Free Fibular Flap in Ameloblastoma of the Mandible-A Need of Time: Our Experience of 37 Cases. Indian J Plast Surg 2020 Dec;53(3):363-70. [DOI:10.1055/s-0040-1719198]
34. Bianchi B, Ferri A, Ferrari S, et al. Mandibular resection and reconstruction in the management of extensive ameloblastoma. J Oral Maxillofac Surg 2013 Mar;71(3):528-37. [DOI:10.1016/j.joms.2012.07.004]
35. Vayvada H, Mola F, Menderes A, Yilmaz M. Surgical management of ameloblastoma in the mandible: Segmental mandibulectomy and immediate reconstruction with free fibula or deep circumflex iliac artery flap (evaluation of the long-term esthetic and functional results). J Oral Maxillofac Surg 2006 Oct;64(10):1532-9. [DOI:10.1016/j.joms.2005.11.065]
36. Ooi A, Feng J, Tan HK, Ong YS. Primary treatment of mandibular ameloblastoma with segmental resection and free fibula reconstruction: achieving satisfactory outcomes with low implant-prosthetic rehabilitation uptake. J Plast Reconstr Aesthet Surg 2014 Apr;67(4):498-505. [DOI:10.1016/j.bjps.2014.01.005]
37. Wang L, Guo K, He K, Zhu H. Bone morphological feature extraction for customized bone plate design. Sci Rep 2021 Aug 2;11(1):15617. [DOI:10.1038/s41598-021-94924-9]
38. Raghoebar, II, Dubois L, de Lange J, et al. The Effectiveness of Three-Dimensional Osteosynthesis Plates versus Conventional Plates for the Treatment of Skeletal Fractures: A Systematic Review and Meta-Analysis. J Clin Med 2023 Jul 13;12(14). [DOI:10.3390/jcm12144661]
39. Kesmez Ö, Valls-Ontañón A, Starch-Jensen T, Haas-Junior OL, Hernández-Alfaro F. Virtual surgical planning in orthognathic surgery with the use of patient-specific plates compared with conventional plates. A systematic review focusing on complications, financial expenses, professional and patient-reported outcome measures. Med Oral Patol Oral Cir Bucal 2022 Nov 1;27(6):e507-e17. [DOI:10.4317/medoral.25424]
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