:: Volume 7, Issue 1 (1-2018) ::
wjps 2018, 7(1): 67-71 Back to browse issues page
The Healing Effect of Sesame Oil, Camphor and Honey on Second Degree Burn Wounds in Rat
Reza Vaghardoost , Gholamreza Mousavi Majd Seyed, Hamid Tebyanian , Hamid Babavalian , Leila Malaei , Mitra Niazi , Ali Javdani
Shahid Motahari Burn Hospital, Iran University of Medical Sciences, Tehran, Iran
Abstract:   (1018 Views)

BACKGROUND
Many studies were carried out to improve sophisticated dressings to accelerate healing processes and reduce the microbial burden in burn wounds. This study evaluated the healing effect of herbal ointment containing extract of sesame oil, camphor and honey on second degree burn wounds in rats in comparison with daily dressing oil vaseline. 
METHODS
Forty rats were randomly assigned to two equal groups. A deep second degree burn was formed on the back of each rat with using a standard burning technique. The burns were dressed daily with herbal ointment containing extract of sesame oil, camphor and honey in group 1, dressing oil vaseline in group 2. The response to treatment was evaluated by digital photography during the treatment on 0, 7, 14, 21, 28 days. Histological scoring was undertaken for scar tissue samples on 0, 7, 14, 21, 28 days. 
RESULTS 
Considerable epithelization in the herbal ointment group vs. the control group over the study period was noted. Neovascularization was significantly higher in herbal ointment treated rats as well. In terms of difference of wound surface area, maximal healing was noticed in herbal ointment extract of sesame oil, camphor and honey group and the minimal repair in the control group. 
CONCLUSION
The greatest rate of healing was in the herbal ointment group containing sesame oil, camphor and honey, so the herbal ointment as a suitable substitute for dressing and healing of burn wound injuries is recommended.  

Keywords: Sesame oil, Camphor, Honey, Burn, Wound, Healing
Full-Text [PDF 1634 kb]   (619 Downloads)    
Type of Study: Original Article | Subject: Special
Received: 2016/11/13 | Accepted: 2018/01/29 | Published: 2018/01/29


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Volume 7, Issue 1 (1-2018) Back to browse issues page