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:: دوره 7، شماره 3 - ( 4-1397 ) ::
جلد 7 شماره 3 صفحات 357-363 برگشت به فهرست نسخه ها
Effect of Pistacia Atlantica Resin Oil on Anti-Oxidant, Hydroxyprolin and VEGF Changes in Experimentally-Induced Skin Burn in Rat
چکیده:   (163 مشاهده)
BACKGROUND
Severe burn damage and its consequences are life threatening which can complicate patients’ health. Medicinal and traditional plants are considered as safe, natural and inexpensive source of treatment for wide variety of diseases. This study assessed beneficial effect of Pistacia atlantica oil on rats burn wound healing and its potential effects on malondialdehyde (MDA), vasculoendothelial growth factor (VEGF), hydroxyprolin and antioxidant status in wound area.
METHODS
Thirty male rats weighing 200±10 g were randomly divided into three groups (n=10) as follows. Group 1 underwent just burn injury, Group 2 underwent burn injury and received 150 mg/kg/day P. atlantica oil topically, and Group 3 underwent burn injury and received 150 mg/kg/day sulfadiazine cream topically. At the end of the study (day 14), wounded areas were measured and then skin in the burn damage were dissected and anti-oxidative parameter, MDA, VEGF and hydroxyprolin were evaluated. 
RESULTS
P. Atlantica oil significantly increased antioxidant defense, VEGF, hydroxyprolin and reduced MDA levels. It could remarkably reduce wound size compared to burn control group. P. Atlantica oil showed more beneficial effects than sulfadiazine.
CONCLUSION
P. atlantica resin oil could be considered as a new therapeutic agent for treatment of injuries. 
متن کامل [PDF 735 kb]   (128 دریافت)    
نوع مطالعه: Short Communication | موضوع مقاله: عمومى
دریافت: 1396/3/11 | پذیرش: 1397/8/11 | انتشار: 1397/8/11
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Shahouzehi B, Sepehri G, Sadeghiyan S, Masoomi-Ardakani Y. Effect of Pistacia Atlantica Resin Oil on Anti-Oxidant, Hydroxyprolin and VEGF Changes in Experimentally-Induced Skin Burn in Rat. wjps. 2018; 7 (3) :357-363
URL: http://wjps.ir/article-1-345-fa.html

Effect of Pistacia Atlantica Resin Oil on Anti-Oxidant, Hydroxyprolin and VEGF Changes in Experimentally-Induced Skin Burn in Rat. مجله جهانی جراحی پلاستیک. 1397; 7 (3) :357-363

URL: http://wjps.ir/article-1-345-fa.html



دوره 7، شماره 3 - ( 4-1397 ) برگشت به فهرست نسخه ها
مجله جهانی جراحی پلاستیک World Journal of Plastic Surgery
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