Volume 1, Issue 2 (2012)                   WJPS 2012, 1(2): 83-90 | Back to browse issues page

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The Synergistic Effect of Bleomycin, Triamcinolone and Epinephrine in Treatment of Hemangioma and Arteriovenous Malformations
Hamid Masiha1 , Heydar Ali Nikpour2 , Mohammad Esmaeil Hasani3 , Abolhasan Emami3 , Mehryar Jafari4 , Ali Manafi 5
1- Private practis Metairie, LA, USA
2- Department of Plastic Surgery, Shiraz University of Medical Sciences, Shiraz, Iran
3- Department of Plastic Surgery, Tehran University of Medical Sciences, Tehran, Iran
4- Medical Student, Tehran University of Medical Sciences, Tehran, Iran
5- Department of Plastic Surgery, Tehran University of Medical Sciences, Tehran, Iran , a-manafi@sina.tums.ac.ir
Abstract:   (9470 Views)
BACKGROUND Hemangioma is the most common tumor of neonatal period and it is almost always appeared by the end of the first week of life and can be found mostly in head and neck area. This study evaluated the synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma and arte-riovenous malformations. METHODS In this multicenter study, a combination of bleomycin, triamcinolone and epinephrine was injected intralesionaly for treatment of hemangiomas and arteriovenous malformations and their synergistic effect was evaluated in 32 patients. RESULTS Hemangiomas and low-flow arteriovenous malformations were treated well with their combination while port-wine spots and high-flow lesions response were relatively poor. CONCLUSION It seems that the combination of bleomycin, triamcinolone and epinephrine may be a good choice in treatment of hemangioma and arteriovenous malformations.
Keywords: Bleomycin; Triamcinolone; Epinephrine; Hemangioma; Arteriovenous malformation
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Type of Study: Original Article | Subject: Special
ePublished: 2014/07/26
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