دوره 8، شماره 2 - ( 1-1398 )                   جلد 8 شماره 2 صفحات 219-228 | برگشت به فهرست نسخه ها


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Motamed S, Mohammadi Torbati P, Zaferani Arani H, Motabar A R, Zabolian A, Madadi Z. Effects of the Human Amniotic Membrane on the Cartilage Graft: Prognosis and Absorption in White Rabbits. wjps. 2019; 8 (2) :219-228
URL: http://wjps.ir/article-1-494-fa.html
Effects of the Human Amniotic Membrane on the Cartilage Graft: Prognosis and Absorption in White Rabbits. مجله جهانی جراحی پلاستیک. 1398; 8 (2) :219-228

URL: http://wjps.ir/article-1-494-fa.html


چکیده:   (681 مشاهده)
BACKGROUND
Cartilage grafts are generally accepted for the restoration and reconstruction of nasal contours. The main concern that plastic surgeons may need to address after surgery pertains to the resorption and disfigurement of the grafted cartilage, especially in allogenic and heterogenic grafts.
METHODS
A total of 12 white rabbits were divided into three groups according to the types of graft including autograft, allograft, and heterograft. We used three shapes of grafts, including block, crushed, and diced cartilage in the upper, middle, and lower rows. However, in each rabbit, these grafts were divided into two columns of wrapped and unwrapped grafts, with human amniotic membrane (HAM) grafted on each side of the rabbit’s back.
RESULTS
In total, 60 specimens underwent histopathological examination. No inflammation was observed in about 50% of the block-shaped conchal cartilages with HAM, and in 50%, less than 25 inflammatory cells per unit were seen. The prognosis and absorption of autograft specimens in block-shaped cartilages with HAM were significantly better compared with other shapes of cartilages with HAM and without HAM. The proliferation rate of fibroblasts in autograft and allograft specimens was more than that in heterograft specimens with HAM.
CONCLUSION
Our findings have demonstrated the new role of HAM in clinical applications, indicating that HAM may be used as a low-cost, easily accessible alternative for wrapping in cartilage grafts instead of fascia or surgicel in early future. It is useful for improving the long-term outcomes and decreasing the resorption rate.
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نوع مطالعه: مقالات اصيل | موضوع مقاله: تخصصي
دریافت: 1398/1/7 | پذیرش: 1398/2/1 | انتشار: 1398/3/28

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