en تخصصي Special مروری Review Article <span style="font-size:12pt"><span style="line-height:150%"><span arial="" style="font-family:"><b><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Background:</span></span></b><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> Maxillofacial fractures are a common type of injury that can result in significant morbidity and mortality. We aimed to systematically review the literature on the prevalence and causes of maxillofacial fractures in Iran to estimate the overall prevalence of maxillofacial fractures and the most common causes. </span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:150%"><span arial="" style="font-family:"><b><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Methods:</span></span></b><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> A systematic search of PubMed, Cochrane Library, Web of Science (WS) and Google Scholar (GS) electronic databases was conducted to identify relevant articles published up to January 2023. Studies reporting the prevalence and causes of maxillofacial fractures in Iran were included in the analysis. MOOSE guidelines were adopted for the current systematic review. No data or language restriction were applied. Risk of bias across the articles was assessed.</span></span><span style="line-height:150%"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:150%"><span arial="" style="font-family:"><b><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Results:</span></span></b><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> A total of 32 studies comprising 35,720 patients were included in the analysis. The most common cause of maxillofacial fractures was road traffic accidents (RTAs), accounting for 68.97% of all cases, followed by falls (12.62%) and interpersonal violence (9.03%). The prevalence of maxillofacial fractures was higher in males (81.04%) and in the age group of 21-30 years (43.23%). Risk of bias across studies was considered low.</span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:150%"><span arial="" style="font-family:"><b><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></b><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> Maxillofacial fractures are a significant public health problem in Iran, with a high prevalence and RTAs being the leading cause. These results highlight the need for increased efforts to prevent maxillofacial fractures in Iran, especially through measures to reduce the incidence of RTAs.</span></span><span style="line-height:150%"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span><br> &nbsp; Iran, Middle East, Maxillofacial Fractures, Prevalence, Systematic Review 3 11 http://wjps.ir/browse.php?a_code=A-10-466-44&slc_lang=en&sid=1 Faeze Sharifi 100319475328460013911 100319475328460013911 No Department of Oral & Maxillofacial Surgery, Mashhad University of Medical Sciences, Mashhad, Iran. Sahand Samieirad 100319475328460013912 100319475328460013912 Yes Department of Oral & Maxillofacial Surgery, Mashhad University of Medical Sciences, Mashhad, Iran. Ricardo Grillo 100319475328460013913 100319475328460013913 No Department of Oral & Maxillofacial Surgery, Traumatology and Prosthesis, University of São Paulo, São Paulo, Brazil. Maria Da Graça Naclério-Homem 100319475328460013914 100319475328460013914 No Department of Oral & Maxillofacial Surgery, Traumatology and Prosthesis, University of São Paulo, São Paulo, Brazil. Erfan Bardideh 100319475328460013915 100319475328460013915 No Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Ali Manafi 100319475328460013916 100319475328460013916 No Department of Plastic Surgery, Iran University of Medical Sciences, Tehran, Iran. Zeinab Mohammadi 100319475328460013917 100319475328460013917 No Department of Medical education, Tehran university of Medical Sciences, Tehran, Iran. Majid Eshghpour 100319475328460013918 100319475328460013918 No Department of Oral & Maxillofacial Surgery, Mashhad University of Medical Sciences, Mashhad, Iran.