en تخصصي Special مروری Review Article <span style="font-size:11pt"><span style="line-height:150%"><span calibri="" style="font-family:"><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Cleft lip and palate is one of the most common congenital malformations of the skull and face (craniofacial). The deformity is characterized by a loss of integrity of the lip muscles, alveolar bone, and hard and soft palate. The severity of the deformity can range from a small hole in the lip to a large fissure extending into the roof of the mouth and nose. Management and control of cleft patients is a challenge. Intervention in these patients begins very early in life, from the fetal period, and continues into adulthood, and the patient&#39;s relatives are always involved in the treatment process. Since there are multiple problems in these patients, the treatment process is managed in a group and multidisciplinary manner to achieve the desired result. The goal of all treatment measures for a person with a cleft lip and palate is to provide intelligible speech, hearing within a normal range, good facial appearance, proper lip and nose symmetry, an attractive smile, good occlusion, healthy oral structures, and ultimately appropriate self-confidence. In the current study, I reviewed the causes, pathophysiology, surgical repair, and treatment approaches in patients with cleft lip and palate.</span></span></span></span></span></span><br> &nbsp; Cleft lip, Cleft palate, Congenital anomalies, Surgery 3 8 http://wjps.ir/browse.php?a_code=A-10-1152-2&slc_lang=en&sid=1 Amir Hossein Alaviyan amirhosseinalavian41@gmail.com 100319475328460017568 0009-0002-4362-0544 Yes Department of General Surgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran