WORLD JOURNAL OF PLASTIC SURGERY

fa The Effect of Ondansetron and Dexamethasone on Nausea and Vomiting under Spinal Anesthesia عمومى General Short Communication Short Communication BACKGROUND During abdominal surgery under regional anesthesia, nausea may happen due to several contributing factors. This study compared the effects of ondansetron and dexamethasone on nausea and vomiting under spinal anesthesia. METHODS One hundred and twenty patients of 15 to 35 years old with ASA class I and II were enrolled. Before administering either ondansetron or dexamethasone, blood pressure and heart rate of the patients were recorded. The patients received 70 mg of 5% lidocaine for spinal anesthesia. Patients who received 6 mg of ondansetron were considered as group A, while group B received 8 mg of dexamethasone. The level of nausea and vomiting, blood pressure, heart rate and respiratory rate of each patient was measured at 1, 5, 10, 15 and 30 minutes after spinal anesthesia and during recovery (every 5 minutes).  RESULTS There was a significant difference between nausea and vomiting between the two groups after spinal anesthesia within the first and fifth minutes. There was no significant difference between nausea and vomiting between the two groups within 10, 15 and 30 minutes and during recovery at 5, 10, 15 and 30 minutes. CONCLUSION Dexamethasone and ondansetron were shown to equally reduce the incidence of nausea and vomiting under spinal anesthesia and can be recommended as a good choice for prevention of nausea and vomiting during surgeries. Ondansetron, Dexamethasone, Nausea, Vomiting, Surgery, Spinal anesthesia 88 93 http://wjps.ir/browse.php?a_code=A-10-1-63&slc_lang=fa&sid=1 Navid Kalani 10031947532846002980 10031947532846002980 No Department of Anesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran Hasan Zabetian h_zabetian@yahoo.com 10031947532846002981 10031947532846002981 Yes Department of Anesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran Mohammad Sadegh Sanie 10031947532846002982 10031947532846002982 No Department of Anesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran Mansour Deylami 10031947532846002983 10031947532846002983 No Department of Anesthesiology, Golestan University of Medical Sciences, Golestan, Iran Mohammad Radmehr 10031947532846002984 10031947532846002984 No Department of Anesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran Reza Sahraei 10031947532846002985 10031947532846002985 No Department of Anesthesiology, Jahrom University of Medical Sciences, Jahrom, Iran Hossein Kargar Jahromi 10031947532846002986 10031947532846002986 No Research Center For Non-Communicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran Wesam Kooti 10031947532846002987 10031947532846002987 No Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran