en تخصصي Special مقالات اصيل Original Article BACKGROUND Hemangioma is the most common tumor of neonatal period and it is almost always appeared by the end of the first week of life and can be found mostly in head and neck area. This study evaluated the synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma and arte-riovenous malformations. METHODS In this multicenter study, a combination of bleomycin, triamcinolone and epinephrine was injected intralesionaly for treatment of hemangiomas and arteriovenous malformations and their synergistic effect was evaluated in 32 patients. RESULTS Hemangiomas and low-flow arteriovenous malformations were treated well with their combination while port-wine spots and high-flow lesions response were relatively poor. CONCLUSION It seems that the combination of bleomycin, triamcinolone and epinephrine may be a good choice in treatment of hemangioma and arteriovenous malformations. Bleomycin; Triamcinolone; Epinephrine; Hemangioma; Arteriovenous malformation 83 90 http://wjps.ir/browse.php?a_code=A-10-1-8&slc_lang=en&sid=1 Hamid Masiha 100319475328460098 100319475328460098 No Private practis Metairie, LA, USA Heydar Ali Nikpour 100319475328460099 100319475328460099 No Department of Plastic Surgery, Shiraz University of Medical Sciences, Shiraz, Iran Mohammad Esmaeil Hasani 1003194753284600100 1003194753284600100 No Department of Plastic Surgery, Tehran University of Medical Sciences, Tehran, Iran Abolhasan Emami 1003194753284600101 1003194753284600101 No Department of Plastic Surgery, Tehran University of Medical Sciences, Tehran, Iran Mehryar Jafari 1003194753284600102 1003194753284600102 No Medical Student, Tehran University of Medical Sciences, Tehran, Iran Ali Manafi a-manafi@sina.tums.ac.ir 1003194753284600103 1003194753284600103 Yes Department of Plastic Surgery, Tehran University of Medical Sciences, Tehran, Iran