en تخصصي Special مروری Review Article <strong>BACKGROUND</strong><br> Antibiotics are commonly used in the treatment of acne vulgaris. Considering the rise of antibiotic resistance, alternative medications may be used in the main anti-acne armamentarium. The aim of this study was to investigate the efficacy of oral azithromycin in the treatment of acne vulgaris.<br> <strong>METHODS</strong><br> Database searches were performed in PubMed and Scopus using the keywords &quot;azithromycin&quot; and &quot;acne&quot;.<br> <strong>RESULTS</strong><br> Azithromycin 500 mg once daily for 3 days per week or in cycles of 10 days for 12 weeks are the most commonly used regimens.<br> <strong>CONCLUSION</strong><br> Available experimental data suggest that oral azithromycin is an effective and well-tolerated option for treatment of acne vulgaris. Azithromycin, Tetracycline, Doxycycline, Acne vulgaris, Treatment 127 134 http://wjps.ir/browse.php?a_code=A-10-142-3&slc_lang=en&sid=1 Sina Kardeh Sinakardeh@gmail.com 10031947532846006875 10031947532846006875 Yes Cellular and Molecular Medicine Student Research Group, School of Medicine, Shiraz University of Medical Science, Shiraz, Iran Nasrin Saki 10031947532846006876 10031947532846006876 No Molecular Dermatology Research Center, Department of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran Farideh Jowkar 10031947532846006877 10031947532846006877 No Molecular Dermatology Research Center, Department of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran Bahareh Kardeh 10031947532846006878 10031947532846006878 No Bone and Joint Diseases Research Center, Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Seyed Arman Moein 10031947532846006879 10031947532846006879 No Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran Mohammad Hossein Khorraminejad-Shirazi 10031947532846006880 10031947532846006880 No Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran