en تخصصي Special مقالات اصيل Original Article BACKGROUND<br> This study was conducted to assess the epidemiology of burn and lethal area of fifty percentage (LA50) in children in Shiraz, Southern Iran.<br> METHODS<br> In this retrospective cross-sectional study, 619 hospitalized burn children from burn centers affiliated to Shiraz University of Medical Sciences, Shiraz, Iran from 2012 to 2016 were enrolled. Demographic characteristics of pa-tients such as age, gender, place and cause of burn, and morality rate were evaluated. LA50 was measured using Probit analysis.<br> RESULTS<br> The mean age of patients was 4.4&plusmn;3.4 years. The mortality rate in burn pa-tients was 8.7% and LA50 of total body surface area (TBSA%) ranged from 40.1% in 2012 to 68.3% in 2016. Although the number of male burn patients (65%) was more than females (35%), the mortality rate in females was more than males (11.4% vs. 7.2%). Scald and flame were the most common causes of burn.<br> CONCLUSION The findings in our burn center comparing burn patients to developed coun-tries showed that LA50 and survival rate were lower denoting to an urgent necessity to promote current policies in burn care and prevention and to de-crease the mortality rate too. Epidemiology, Burn, LA50, Children, Iran 66 70 http://wjps.ir/browse.php?a_code=A-10-466-13&slc_lang=en&sid=1 Seyedeh-Sara Hashemi 100319475328460010030 100319475328460010030 No Burn and Wound Healing Research Center, Shiraz University of Medical Science, Shiraz, Iran Mahdukht Mahmoodi 100319475328460010031 100319475328460010031 No Burn and Wound Healing Research Center, Shiraz University of Medical Science, Shiraz, Iran Hamid Reza Tohidinik 100319475328460010032 100319475328460010032 No Burn and Wound Healing Research Center, Shiraz University of Medical Science, Shiraz, Iran Ali Akbar Mohammadi 100319475328460010033 100319475328460010033 Yes Burn and Wound Healing Research Center, Shiraz University of Medical Science, Shiraz, Iran Davood Mehrabani 100319475328460010034 100319475328460010034 No Stem Cell Technology Research Cen-ter, Shiraz University of Medical Sci-ences, Shiraz, Iran