WORLD JOURNAL OF PLASTIC SURGERY
مجله جهانی جراحی پلاستیک
WJPS
Medical Sciences
http://wjps.ir
1
admin
2228-7914
2252-0724
8
10.61186/wjps
14
8888
13
en
jalali
1399
10
1
gregorian
2021
1
1
10
1
online
1
fulltext
en
The Comparison of Clinical and Histopathological Effects of Topical Psyllium (Plantago ovata) Powder and Silver Sul-fadiazine on Second-Degree Burn Wound Healing in Rats
تخصصي
Special
مقالات اصيل
Original Article
BACKGROUND<br>
Burn wounds are a worldwide health problem, leading to physical and psycholog-ical disabilities in all age’s groups. With regard to absorbent properties of Planta-go ovata mucilage which can decrease wound moisture, we aimed to compare the effect of silver sulfadiazine (SSD) 1% and powdered P. ovata on second-degree burn wound healing in rats.<br>
METHODS<br>
This experimental study was conducted on 30 male Wistar rats with second-degree burn in three groups. Group 1 (control) did not receive any treatment; group 2 and group 3 (treated groups) were dressed daily using SSD cream and P. ovata powder, respectively. The weight of rats, wound size (by applying ImageJ software) and percentage of wound healing on the 5th, 7th, 10th, 13th, 16th, 19th, and 22nd days (by diagnosing a plastic surgeon) and histological cutaneous changes at day 22 were evaluated. The Prism software was applied for data analysis. The Haematoxylin & Eosin as well as Masson's trichrome staining were performed on wound skin biopsies.<br>
RESULTS<br>
On day 22nd, 20%, 50% and 60% of the rats had complete wound healing in the control, SSD and P. ovata groups, respectively. A significant decrease in wound size was shown in the treated groups compared to the control group (P<0.01), but no significant difference was shown between the treated groups (P>0.05). CONCLUSION However, the wound healing in P. ovata group or SSD was better than the control group, and the significant difference was not found with the treated group.
Burn, Plantago ovata, Rat, Silver sulfadiazine, Wound
96
103
http://wjps.ir/browse.php?a_code=A-10-466-15&slc_lang=en&sid=1
Mohammad
Jalilimanesh
100319475328460010003
100319475328460010003
Yes
Herbal Medicine Research Center, School of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Maryam
Azhdari
100319475328460010004
100319475328460010004
No
Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Aghdas
Mirjalili
100319475328460010005
100319475328460010005
No
Department of Plastic and Reconstructive Surgery, Shohadaye Mehrab Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran;
Mohammad Ali
Mozaffari
100319475328460010006
100319475328460010006
No
Shahid Beheshti University Student Research Center, Tehran, Iran
Seyedhossein
Hekmatimoghaddam
100319475328460010007
100319475328460010007
No
Department of Advanced Medical Sciences and Technologies, School of Paramedicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran