WORLD JOURNAL OF PLASTIC SURGERY
Sat, Apr 20, 2024
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Volume 11, Issue 1 (2022)
WJPS 2022, 11(1): 138-140 |
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Selvaraj D R, Adjei B, Farooq AL-NAHHAS O, Kamil L, Yonjan I. A Rare Case of a Chemical Burn: Dithranol with Salicylic Acid. WJPS 2022; 11 (1) :138-140
URL: http://wjps.ir/article-1-856-en.html
URL: http://wjps.ir/article-1-856-en.html
1- Department of Plastic Surgery, Aberdeen Royal Infirmary, Aberdeen, Scotland, United Kingdom
Abstract: (2320 Views)
A 16-year-old female with psoriasis presented to our Plastic Surgery Department with a significant chemical burn to the neck, upper torso and left cheek (TBSA 6%). She applied a concoction of cream prescribed by her dermatologist in her native country, Poland when she returned to the United Kingdom. A few hours after application she developed a burn with pH of 5. A review of the cream revealed a mixture of 19% dithranol and 5% salicylic acid. This combination is recognized for managing psoriasis, however the strength of dithranol in the combination given is of a high concentration (normally <3%). This alone can cause a burn to the skin if left for a prolonged period of time. Salicylic acid is an enhancer which augments the stability of dithranol and increases its penetration and efficacy. The concentration of 5% is also on the higher end. Our patient was admitted for pain relief and further irrigation till normalization of the pH which was achieved after 3 days. A worrying aspect in our patients’ case is that she was given the cream to commence at home. High concentration preparation is normally commenced in a controlled setting under medical supervision.
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