Showing 12 results for Shahrokh
Davood Mehrabani, Golshid Mehraban, Shahrokh Zare, Ali Manafi,
Volume 2, Issue 2 (7-2013)
Abstract
In cell therapy and regenerative medicine, a reliable source of stem cells together with cytokine growth factors and biomaterial scaffolds seem necessary. As adipose tissue is easy accessible and is abundant source of adult stem cells and can differentiate along multiple lineages, it can be considered as a good candidate in aesthetic medicine. The clinical application of adipose-derived stem cells (ASCs) is reviewed in this article.
Davood Mehrabani, Fereidoon Mojtahed Jaberi, Maryam Zakerinia, Mohammad Javad Hadianfard, Reza Jalli, Nader Tanideh, Shahrokh Zare,
Volume 5, Issue 2 (4-2016)
Abstract
Osteoarthritis (OA) is a prevalent chronic disease impacting on quality of life and has societal and economical burden increasing with age. Yet, no confirmed pharmacological, biological or surgical therapy could prevent the progressive destruction of OA joint. Mesenchymal stem cells (MSCs) with immunosuppressive activities emerged a potential therapy. We describe a magnetic resonance images (MRI) approved 47 years old nomad female suffering from a severe right knee OA. After intra-articular injection of 36×106 passage 2 of bone marrow-derived stem cells (BMSCs), the patient’s functional status of the knee, the number of stairs she could climb, the pain on visual analog scale (VAS) and walking distance improved after two months post-transplantation. MRI revealed an extension of the repaired tissue over subchondral bone. So as MSC transplantation is a simple technique, resulted into pain relief, minimized donor-site morbidity, provided a better quality of life, significantly improved cartilage quality with no need to hospitalization or surgery, cell transplantation can be considered as a reliable alternative treatment for chronic knee OA. Therefore these findings can be added to the literature on using BMSCs for treatment of OA.
Shahrokh Attarian, Afsaneh Karami, Faezeh Ayatolahi,
Volume 6, Issue 1 (1-2017)
Abstract
Shahrokh Attarian, Fereidoon Sirati,
Volume 6, Issue 2 (4-2017)
Abstract
Kamyar Iravani, Arash Sobhanmanesh, Mohammad Javad Ashraf, Seyed Basir Hashemi, Davood Mehrabani, Shahrokh Zare,
Volume 6, Issue 2 (4-2017)
Abstract
BACKGROUND
Differences in causes, severities, areas of stenosis, and the association with swallowing and phonation of larynx and trachea can result into Laryngotracheal stenosis (LTS).This study evaluated the healing effect of bone marrow stem cells (BMSCs) in experimentally induced LTS dog model.
METHODS
<span style="font-size:12.0pt;line-height:200%;mso-ascii-font-family: " times="" new="" roman";mso-ascii-theme-font:major-bidi;mso-hansi-font-family:"times="" roman";="" mso-hansi-theme-font:major-bidi;mso-bidi-font-family:"times="" mso-bidi-theme-font:major-bidi"="">Seven dogs were enrolled. BMSCs were isolated from proximal humerus and shoulder of a dog and cultured in media containing alpha minimal essential medium, fetal bovine serum, penicillin and streptomycin, and L-glutamine. BMSCs were characterized morphologically, by RT-PCR, and osteogenic induction. Karyotyping was undertaken for chromosomal stability. Mechanical trauma to laryngeal mucosa was identically conducted by Tru-cut punch forceps in right and left vocal folds. Two milliliter of conditioned media or BMSCs (2×106) were injected in the right site of the tissue and the left side was considered as control after LTS induction. The larynx was visualized 2, 4 and 6 weeks after treatment. Six weeks post-treatment, the larynges were evaluated histologically.
RESULTS
BMSCs were adhered to culture flasks, spindle shape and positive for mesenchymal marker and negative for hematopoietic markers. Osteogenic induction was verified by Alizarin red staining. Karyotype was normal. A complete epithelialization and minimal chronic inflammatory cell infiltration were noted in submucosa of both left (control) and right (cases) vocal folds. The healing effect of conditioned media and BMSCs in comparison to the control group was more prominent.
CONCLUSION
As thickness of fibrosis in cases were less than control group, conditioned media and BMSCs were shown to be good choices in healing of LTS.
Abdoljalil Kalantar-Hormozi, Soraya Shahrokh, Ali Abbaszadeh-Kasbi, Nazanin Rita Davai,
Volume 8, Issue 1 (1-2019)
Abstract
BACKGROUND
The demand for facial plastic surgery has dramatically been increased in recent years. Over the last decade, numerous methods have been improved for facelift surgery. Despite these modifications, skin excision technique has not changed significantly. In this study, authors have tried to introduce a new technique regarding skin excision at the initial step of facelift surgery.
METHODS
A prospective study from 2012 to 2017 on 52 patients was carried out to apply a new technique for facelift ‘’Prefabricated skin excision method’’ for all eligible patients undergoing facelift surgery. The skin calling for excision was marked by the surgeon, and then, an analgesic drug was administered. Then, excision of the marked part of the skin was performed and afterward the dissection of the superficial musculoaponeurotic system (SMAS) was performed with the direct exposure.
RESULTS
All patients were female, and 50 (96.1%) cases were primary face lift and 2 (3.9%) cases were secondary. There were no complications among the patients.
CONCLUSION
Facilitating the manipulation of deep layer, using this technique led to the further exposure of the surgical site, and more preferable hemostasis was achieved as well.
Maryam Iranpour, Ali Khodarahmi, Maryam Beigi, Omid Azari, Soraya Shahrokh Shahraki,
Volume 11, Issue 1 (3-2022)
Abstract
BACKGROUND
A suitable pharmacological substitute for the well-established surgical delay technique for axial skin flaps regarding increasing viability is elusive. We aimed to evaluate the effects of botulinum toxin type A (BTA) on the axial skin flap survival in a rat model.
METHODS
The present controlled experimental study was performed in Kerman University of Medical Science, Kermanshah, Iran during 2016-2017 on three groups of rats. Group 1 (control group) had no preconditioning while Groups 2 and 3 were preconditioned by the intradermal injection of normal saline (0.5 ml) in the cephalic end of the skin flap and the injection of the BTA (1.6 units Neuronex) reconstituted in normal saline, respectively. Two weeks after this intervention in each group, the flap was raised and kept in situ and a biopsy was simultaneously taken for evaluating neoangiogenesis, followed by evaluating flap necrosis after two weeks of following-up by photography.
RESULTS
Although BTA induced angiogenesis significantly, it failed to reduce the area of necrosis compared to the other groups.
CONCLUSION
BTA was effective in increasing angiogenesis in the axial skin flap although it was unable to reduce necrosis.
Soraya Shahrokh Shahraki, Masoud Yavari, Ali Tabrizi,
Volume 11, Issue 2 (7-2022)
Abstract
BACKGROUND
Preventing perineural adhesions and scars formation in the traumatic peripheral injuries is very important on the recovery process. We aimed to evaluate the effect of using the amniotic membrane wrapping on the results of surgical treatment of damaged peripheral nerves.
METHODS
This cohort study included 30 patients with symptoms of acute peripheral nerve injuries due to penetrating trauma in the forearm or wrist in January 2019 to November 2020 referred to the Hand and Microsurgery Department, 15 Khordad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. In 15 patients, after nerve repair, amniotic membrane coverage was used around the nerve, all patients were followed for 12 months. Ultrasound study for neuroma formation and nerve regeneration was determined based on EMG and NCV findings. The modified Medical Research Councile classification (MRCC) was used to evaluate of motor and sensory recovery.
RESULTS
In the amniotic membrane wrapping group, all patients had nerve regeneration and functional nerve recovery occurred after 12 months. In the control group, 5 patients (33.4%) did not have nerve recovery and had functional and sensory impairment. In terms of functional capabilities; there was a significant difference in pinch strength, grip power and MRCC scoring between the two groups. Moreover, the mean volume of neuroma in these patients who used amniotic membrane covering was 2.7 mm3 and in the control group, it was 3.9 mm3 (P=0.001). Five patients who did not have a damaged nerve, the neuroma volume was 4.8 ± 0.9 mm3.
CONCLUSION
The use of amniotic membrane covering is effective methods in the improve results of peripheral nerve repair and nerve function recovery.
Masoud Yavari, Soraya Shahrokh Shahraki, Seyed Mehdi Mousavizadeh, Arian Karimi Rouzbahani, Golnaz Mahmoudvand, Hadi Sedghi Asl,
Volume 11, Issue 3 (8-2022)
Abstract
Background: Brachial plexus injury (BPI) is a severe peripheral nerve injury resulting in physical disability. Few studies have investigated the postoperative functional status. We aimed to evaluate the satisfaction with surgical treatment in patients with BPI referred to the Panzdah-e Khordad Hospital, Tehran, Iran from 2011 to 2021.
Methods: In this descriptive-analytical retrospective comparative study, physical examination, along with BrAT, and DASH questionnaires were used to evaluate the patients’ status. Then the collected data on the patients’ functional status and movements were collected. To compare the mean of quantitative variables before and after the surgery, the dependent t-student was used.
Results: Generally, the patients stated that they still had considerable difficulty doing most of the items of the questionnaires. Nevertheless, there was a significant difference between the following variables before and after surgery; shoulder abduction goniometry (0-150) and force (M0:M5), shoulder external rotation goniometry (0-90) and force (M0:M5)), shoulder forward flexion goniometry (0-180) and force (M0:M5)), elbow flexion goniometry (0- 150), elbow extension force (M0:M5), and wrist and finger muscle force (M0:M5) (P<0.001).
Conclusion: Posterior approach in BPI surgery was associated with good outcomes in terms of shoulder external rotation and abduction. However, patients still suffered from difficulties in daily activities.
Zohreh Khoshgoftar, Soraya Shahrokh Shahraki, Shirin Araghi, Samaneh Tahmasebi Ghorabi, Golnaz Mahmoudvand, Arian Karimi Rouzbahani,
Volume 12, Issue 2 (5-2023)
Abstract
Background: Clinical educational environments play a substantial role in the teaching of medical residents and fellows. In order to improve the quality of clinical education, its status should be evaluated. Therefore, we aimed to inquire about the educational environment of Plastic Surgery fellows in two teaching hospitals in Tehran, Iran using the Postgraduate Hospital Educational Environment Measure (PHEEM).
Method: In this descriptive cross-sectional study, Plastic Surgery fellows studying in two teaching hospitals in Tehran, Iran, in 2022 were included. The Persian version of the PHEEM questionnaire was applied for assessing the clinical educational environment. The collected data were analyzed by SPSS software version 22.
Results: Twenty six Plastic Surgery fellows were studied, 15.4% of whom were women (n=4) and 84.6% were men (n=22). The mean total score of the PHEEM questionnaire was 89.68±26.02. The highest mean score was in the teaching dimension (35.08), while the lowest mean score was in the social support dimension (25.42).
Conclusion: Most dissatisfaction among Plastic Surgery fellows were in the field of social support. It is necessary to adopt proper educational policies to improve the supportive resources for Plastic Surgery fellows.
Background: Clinical educational environments play a substantial role in the teaching of medical residents and fellows. In order to improve the quality of clinical education, its status should be evaluated. Therefore, we aimed to inquire about the educational environment of Plastic Surgery fellows in two teaching hospitals in Tehran, Iran using the Postgraduate Hospital Educational Environment Measure (PHEEM).
Method: In this descriptive cross-sectional study, Plastic Surgery fellows studying in two teaching hospitals in Tehran, Iran, in 2022 were included. The Persian version of the PHEEM questionnaire was applied for assessing the clinical educational environment. The collected data were analyzed by SPSS software version 22.
Results: Twenty six Plastic Surgery fellows were studied, 15.4% of whom were women (n=4) and 84.6% were men (n=22). The mean total score of the PHEEM questionnaire was 89.68±26.02. The highest mean score was in the teaching dimension (35.08), while the lowest mean score was in the social support dimension (25.42).
Conclusion: Most dissatisfaction among Plastic Surgery fellows were in the field of social support. It is necessary to adopt proper educational policies to improve the supportive resources for Plastic Surgery fellows.
Khalil Rostami, Amirhossein Karimi, Soraya Shahrokh,
Volume 14, Issue 1 (3-2025)
Abstract
Background: Abdominoplasty surgery is associated with intra-abdominal pressure (IAP) and respiratory airway pressure (RAP) changes. We aimed to assess the impact of the lipoabdominoplasty on the simultaneous changes in the IAP and RAP and their predictive factors for the first time.
Methods: This prospective study was conducted on 30 women who underwent lipoabdominoplasty between November 2021 and November 2022 in Modares and 15- Khordad hospitals affiliated with Shahid Beheshti University of Medical Sciences, Tehran, Iran. Patients underwent lipoabdominoplasty by a surgeon with more than ten years of experience. RAP was measured based on P platue and P Peak three times (after anesthesia, after plication, and after surgery).
Results: The mean changes of IAP and RAP were significantly different based on the p peak and p plateau after anesthesia, plication, and surgery (P<0.001). Changes in IAP with BMI, degree of laxity, degree of plication, number of pregnancies, xiphoid to pubis distance, and 12th vertebra to ASIS distance were related. RAP (p peak and P platue) with a degree of laxity, degree of plication, number of pregnancies, IAP, xiphoid to pubis distance, and 12th vertebra to ASIS distance were related (P<0.05).
Conclusion: lipoabdominoplasty significantly affects changes in IAP and RAP after anesthesia, plication, and surgery. During lipoabdominoplasty, surgeons should simultaneously pay attention to the changes in both IAP and RAP from the beginning to the end of the surgery, especially in obese women with a history of multiple pregnancies and patients with severe laxity.
Soraya Shahrokh Shahraki, Farnood Gharghabi, Masoud Yavari,
Volume 14, Issue 1 (3-2025)
Abstract
Background: We investigated the therapeutic outcomes of trapezius muscle transfer in individuals diagnosed with brachial plexus damage.
Methods: We examined patients diagnosed with brachial plexus palsy referred to 15 Khordad Hospital in Tehran, Iran during 2018-20. The patients considered for inclusion in the study were those who were eligible for trapezius muscle transfer surgery, either on the affected side or the unaffected side. The evaluation focused on various aspects, including shoulder range of motion, muscle strength, shoulder pain, age and gender distribution, as well as satisfaction and function levels of the shoulder.
Results: The suitability of shoulder motions, shoulder abduction, and muscular strength in patients who underwent ipsilateral side trapezius muscle transfer surgery was greater compared to those who underwent contralateral side trapezius transfer. In the investigation of postoperative shoulder function among patients who underwent trapezius muscle transfer surgery on the ipsilateral side, it was shown that 3 patients (25%) exhibited favorable function, while 6 patients (50%) demonstrated acceptable function, and 3 patients (25%) displayed excellent function. Out of the total sample size of 9 patients who underwent surgery for trapezius muscle transfer on the contralateral side, 6 patients (66.7%) exhibited favorable function, while 3 patients (33.3%) demonstrated acceptable function.
Conclusion: Employing the contralateral trapezius muscle as a substitute when utilizing the ipsilateral trapezius muscle is not feasible is a viable alternative with favorable function.
