en تخصصي Special گزارش مورد case report <span style="font-size:11pt"><span style="text-justify:inter-ideograph"><span style="line-height:200%"><span sans-serif="" style="font-family:Calibri,"><span lang="EN-MY" style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times=""><span style="color:#0e101a"></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:inter-ideograph"><span style="line-height:200%"><span sans-serif="" style="font-family:Calibri,"><span lang="EN-MY" style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times=""><span style="color:#0e101a">Necrotising fasciitis (NF) is a rare, severe, rapidly progressive, and life-threatening synergistic infection that primarily affects the superficial fascia. Although unusual in head and neck surgeries, necrotizing fasciitis may have drastic consequences. Dental problems, burns, trauma, and peritonsillar abscesses often cause the condition. We describe a rare case of extensive facial necrotising fasciitis secondary to carbimazole&ndash;induced agranulocytosis. A protective tracheostomy, prophylactic thyroidectomy, serial surgical debridement, and broad-spectrum antibiotics therapy were initiated. Our team referred the patient for subsequent soft tissue reconstruction. Reconstruction was challenging as it involved a full-thickness cheek defect extending to the oral commissure, lower lip, and anterior neck. In a single-stage procedure, we utilised a transverse upper gracilis free flap to reconstruct full-thickness tissue loss, provide tissue bulk, and seal the dead space. Reconstructing various parts of the face and lips while ensuring aesthetic and functional results can be difficult.</span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="text-justify:inter-ideograph"><span style="line-height:200%"><span sans-serif="" style="font-family:Calibri,"><span lang="EN-MY" style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times=""><span style="color:#0e101a"></span></span></span></span></span></span></span></span><br> &nbsp; Carbimazole-induced agranulocytosis, Necrotising fasciitis, Lip reconstruction, Microsurgery 93 96 http://wjps.ir/browse.php?a_code=A-10-898-3&slc_lang=en&sid=1 Hui Yuan Lam 100319475328460016520 100319475328460016520 Yes Department of Plastic Reconstructive Surgery, Hospital Kuala Lumpur, 50586, Kuala Lumpur, Malaysia Hamidah Binti Mohd Zainal 100319475328460016521 100319475328460016521 No Department of Plastic Reconstructive Surgery, Hospital Kuala Lumpur, 50586, Kuala Lumpur, Malaysia Khai Luen Koh kkhailuen@moh.gov.my 100319475328460016522 100319475328460016522 No Department of Plastic Reconstructive Surgery, Hospital Kuala Lumpur, 50586, Kuala Lumpur, Malaysia Mohammad Ali Bin Mat Zain 100319475328460016523 100319475328460016523 No Department of Plastic Reconstructive Surgery, Hospital Kuala Lumpur, 50586, Kuala Lumpur, Malaysia