en تخصصي Special مقالات اصيل Original Article Background:<br> Tumescent local anaesthesia with prilocain can lead to clinically significant methemoglobin levels. New generation multiple wavelength pulse oximeters (e. g. Masimo Radical 7^&reg;) can measure methemoglobin levels.<br> Methods:<br> In this prospective observational study we compared the venous methemoglobin levels and the corresponding pulse oximetric values of the Radical 7^&reg; in patients undergoing tumescent local anaesthesia for liposuction procedures. The measurements were performed in Hanseklinik, Luebeck, Germany between 2008 and 2011.<br> Results:<br> In 133 patients, we measured a maximum methemoglobin level of 18 per cent. In a Bland-Altman analysis we found a mean bias of +2.2 % (-4.1 to 8.4 limits of agreement) for pulse oximetric values compared to hemoximetry.<br> Conclusion:<br> Pulse oximetric measurement of methemoglobin is an early-warning tool for the detection of clinically significant methaemoglobinemia in patients with tumescent local anaesthesia. Tumescent anaesthesia, Methaemoglobinemia, Pulse oximetry, Liposuction 111 116 http://wjps.ir/browse.php?a_code=A-10-684-2&slc_lang=en&sid=1 Sebastian Brandt sebastian.brandt@uksh.de 100319475328460012493 100319475328460012493 Yes Department of Anaesthesiology, University Medical Center Schleswig-Holstein, Campus Luebeck, Luebeck, Germany Oliver Kimberger 100319475328460012494 100319475328460012494 No Department of Anaesthesiology, Medical University of Vienna, Vienna, Austria Benjamin Weber 100319475328460012495 100319475328460012495 No Medical Sensors and Devices Laboratory, Luebeck University of Applied Sciences, Luebeck, Germany Anne Klose 100319475328460012496 100319475328460012496 No Department of Anaesthesiology, Schoenklinik Neustadt, Neustadt, Germany Swetlana Stockmann 100319475328460012497 100319475328460012497 No Institute of Clinical Chemistry, University Medical Center Schleswig-Holstein, Campus Luebeck, Luebeck, Germany Wilfried Schmeller 100319475328460012498 100319475328460012498 No Hanse-Klinik Luebeck, Luebeck, Germany Hartmut Gehring 100319475328460012499 100319475328460012499 No Department of Anaesthesiology, University Medical Center Schleswig-Holstein, Campus Luebeck, Luebeck, Germany Patrick Kellner 100319475328460012500 100319475328460012500 No Department of Anaesthesiology, University Medical Center Schleswig-Holstein, Campus Luebeck, Luebeck, Germany