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:: Volume 4, Issue 1 (1-2015) ::
wjps 2015, 4(1): 50-59 Back to browse issues page
Comparison between Conventional Mechanical Fixation and Use of Autologous Platelet Rich Plasma (PRP) in Wound Beds Prior to Resurfacing with Split Thickness Skin Graft
Veena P Waiker Dr , Shanthakumar Shivalingappa Dr
M.B.B.S,M.S,M.ch
Abstract:   (3504 Views)
BACKGROUND Platelet rich plasma is known for its hemostatic, adhesive and healing properties in view of the multiple growth factors released from the platelets to the site of wound. The primary objective of this study was to use autologous platelet rich plasma (PRP) in wound beds for anchorage of skin grafts instead of conventional methods like sutures, staplers or glue. METHODS In a single center based randomized controlled prospective study of nine months duration, 200 patients with wounds were divided into two equal groups. Autologous PRP was applied on wound beds in PRP group and conventional methods like staples/sutures used to anchor the skin grafts in a control group. RESULTS Instant graft adherence to wound bed was statistically significant in the PRP group. Time of first post-graft inspection was delayed, and hematoma, graft edema, discharge from graft site, frequency of dressings and duration of stay in plastic surgery unit were significantly less in the PRP group. CONCLUSION Autologous PRP ensured instant skin graft adherence to wound bed in comparison to conventional methods of anchorage. Hence, we recommend the use of autologous PRP routinely on wounds prior to resurfacing to ensure the benefits of early healing.
Keywords: Platelet rich plasma, Hemostasis, Skin graft, Edema
Full-Text [PDF 2766 kb]   (1581 Downloads)    
Type of Study: Original Article | Subject: General
Received: 2014/10/31 | Accepted: 2014/12/17 | Published: 2014/12/17
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Waiker V P, Shivalingappa S. Comparison between Conventional Mechanical Fixation and Use of Autologous Platelet Rich Plasma (PRP) in Wound Beds Prior to Resurfacing with Split Thickness Skin Graft. wjps. 2015; 4 (1) :50-59
URL: http://wjps.ir/article-1-124-en.html


Volume 4, Issue 1 (1-2015) Back to browse issues page
مجله جهانی جراحی پلاستیک World Journal of Plastic Surgery
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