Lam H Y, Zainal H B M, Koh K L, Zain M A B M. The Challenges of Extensive Face and Neck Necrotising Fasciitis Reconstruction: A Case Report. WJPS 2025; 14 (1) :93-96
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http://wjps.ir/article-1-1372-fa.html
چکیده: (333 مشاهده)
Necrotising fasciitis (NF) is a rare, severe, rapidly progressive, and life-threatening synergistic infection that primarily affects the superficial fascia. Although unusual in head and neck surgeries, necrotizing fasciitis may have drastic consequences. Dental problems, burns, trauma, and peritonsillar abscesses often cause the condition. We describe a rare case of extensive facial necrotising fasciitis secondary to carbimazole–induced agranulocytosis. A protective tracheostomy, prophylactic thyroidectomy, serial surgical debridement, and broad-spectrum antibiotics therapy were initiated. Our team referred the patient for subsequent soft tissue reconstruction. Reconstruction was challenging as it involved a full-thickness cheek defect extending to the oral commissure, lower lip, and anterior neck. In a single-stage procedure, we utilised a transverse upper gracilis free flap to reconstruct full-thickness tissue loss, provide tissue bulk, and seal the dead space. Reconstructing various parts of the face and lips while ensuring aesthetic and functional results can be difficult.
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تخصصي انتشار الکترونیک: 1404/1/16
فهرست منابع
1. Chou PY, Hsieh YH, Lin CH. Necrotizing fasciitis of the entire head and neck: Literature review and case report. Biomed J 2020;43(1):94-98. doi:10.1016/j.bj.2019.08.002 [
DOI:10.1016/j.bj.2019.08.002]
2. Ahmadzada S, Rao A, Ghazavi H. Necrotizing fasciitis of the face: current concepts in cause, diagnosis and management. Curr Opin Otolaryngol Head Neck Surg 2022;30(4):270-275. doi:10.1097/MOO.0000000000000820 [
DOI:10.1097/MOO.0000000000000820]
3. Pearce SH. Spontaneous reporting of adverse reactions to carbimazole and propylthiouracil in the UK. Clin Endocrinol (Oxf) 2004;61(5):589-594. doi:10.1111/j.1365-2265.2004.02135.x [
DOI:10.1111/j.1365-2265.2004.02135.x]
4. Cooper DS. Antithyroid drugs. N Engl J Med 2005;352(9):905-917. doi:10.1056/NEJMra042972 [
DOI:10.1056/NEJMra042972]
5. Mohan A, Joseph S, Sidharthan N, Murali D. Carbimazole-induced agranulocytosis. J Pharmacol Pharmacother 2015;6(4):228-230. doi:10.4103/0976-500X.171881 [
DOI:10.4103/0976-500X.171881]
6. Andrès E, Zimmer J, Mecili M, Weitten T, Alt M, Maloisel F. Clinical presentation and management of drug-induced agranulocytosis. Expert Rev Hematol 2011;4(2):143-151. doi:10.1586/ehm.11.12 [
DOI:10.1586/ehm.11.12]
7. del Giudice P, Cua E, Bernard E, et al. Pseudomonas aeruginosa ecthyma gangrenosum and facial cellulitis complicating carbimazole-induced agranulocytosis. Arch Dermatol 2006;142(12):1663-1664. doi:10.1001/archderm.142.12.1663 [
DOI:10.1001/archderm.142.12.1663]
8. Cheng HT, Lin FY. Pseudomonas aeruginosa necrotizing fasciitis in a patient with methimazole-induced agranulocytosis. Am Surg 2011; 77(11):1561-1562. [
DOI:10.1177/000313481107701151]
9. Kauff, Dw & Staubitz, Julia & Musholt, Thomas & Lang, Hauke. Synchronous Antithyroid Drug-Induced Agranulocytosis and Fournier Gangrene. AACE Clinical Case Reports 2017. 4. 10.4158/EP171801.CR. [
DOI:10.4158/EP171801.CR]
10. Calderon W, Chang N, Mathes SJ. Comparison of the effect of bacterial inoculation in musculocutaneous and fasciocutaneous flaps. Plast Reconstr Surg 1986;77(5):785-794. doi:10.1097/00006534-198605000-00016 [
DOI:10.1097/00006534-198605000-00016]