Volume 11, Issue 2 (7-2022)                   WJPS 2022, 11(2): 57-61 | Back to browse issues page


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Hormozi A K, Kasbi A A, Hormozi H K, Davai N R. Assessing Long-Term Neurodevelopment among Children with Non-Syndromic Single Suture Craniosynostosis. WJPS. 2022; 11 (2) :57-61
URL: http://wjps.ir/article-1-940-en.html
Department of Plastic and Craniofacial Surgery, 15 Khordad Hospital, Medical College of Shahid Beheshti University of Medical Science (SBMU), Tehran, Iran , kalantarj@yahoo.com
Abstract:   (219 Views)
Background: Single suture craniosynostosis (SSC) is a disorder, affecting brain growth. Reviewing literature reveals controversialists of papers in this field.
Methods: This prospective study was conducted from 2014 to 2016. All the individuals, aged 2 to 16 years, whose medical records files were complete, with SSC from 1999 to 2013 were included. All patients had undergone cranial vault remodeling at Mofid Hospital, Tehran, Iran. Wechsler questionnaires, WPPSI-III and WISC-IV, were completed for each child based on his/her age.
Results: Seventy children were included, with the mean age of 6.7 (±2.9) years. Forty-six (65.7%) children were boys while 24 (34.3%) were girls. Mean FSIQ for all of children was 95.5 (±13.2). Mean verbal IQ, performance IQ, verbal comprehension, perceptual reasoning, processing speed, and working memory are 93.4 (±14.1), 96.1 (±13.3), 97.5 (±13.9), 102.2 (±12.5), 94.5 (±9.8), and 97.5 (±12.9), respectively. There was statistically significant difference between FSIQ of children with SSC and that of unaffected children (P-value<0.05). There was significant difference between verbal IQ of children with SSC and that of unaffected ones (P-value< 0.007). There was significant difference between in processing speed between affected children and unaffected children (P-value<0.012).
Conclusion: Children, aged 2 to 6 years, with SSC had a significantly lower Verbal IQ, and children, aged 6 to 16 years, with SSC had a significantly lower processing speed than their healthy counterparts. Though FSIQ of children with SSC falls within normal range, it is a little lower than healthy peers.
 
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Type of Study: Original Article | Subject: Special
Received: 2022/07/15 | Accepted: 2022/07/19 | Published: 2022/07/30

References
1. Knight SJ, Anderson VA, Spencer-Smith MM, Da Costa AC. Neurodevelopmental outcomes in infants and children with single-suture craniosynostosis: a systematic review. Dev Neuropsychol 2014;39(3):159-186. [DOI:10.1080/87565641.2014.886690] [PMID]
2. Aldridge K, Birgfeld C, Austin JR, Regina YM, et al. Structural brain differences in school-age children with and without single-suture craniosynostosis. J Neurosurg Pediatr 2017;19(4):479-489. [DOI:10.3171/2016.9.PEDS16107] [PMID] [PMCID]
3. Cornelissen M, Ottelander B, Rizopoulos D, Hulst RVD, Molen AMVD, Horst CVD, et al. Increase of prevalence of craniosynostosis. J Craniomaxillofac Surg. 2016;44(9):1273-1279. [DOI:10.1016/j.jcms.2016.07.007] [PMID]
4. Tahiri Y, Bartlett SP, Gilardino MS. Evidence-Based Medicine: Nonsyndromic Craniosynostosis.
5. Plast Reconstr Surg 2017;140(1):177e-191e. [DOI:10.1097/PRS.0000000000003473] [PMID]
6. Timberlake AT, Persing JA. Genetics of Nonsyndromic Craniosynostosis. Plast Reconstr Surg 2018;141(6):1508-1516. [DOI:10.1097/PRS.0000000000004374] [PMID]
7. Governale LS. Craniosynostosis. Pediatr Neurol 2015;53(5):394-401. [DOI:10.1016/j.pediatrneurol.2015.07.006] [PMID]
8. Spruijt B, Joosten KF, Driessen C, Rizopoulos D, Naus NC, Schroeff MP, et al. Algorithm for the Management of Intracranial Hypertension in Children with Syndromic Craniosynostosis. Plast Reconstr Surg 2015;136(2):331-340. [DOI:10.1097/PRS.0000000000001434] [PMID]
9. Speltz ML, Collett BR, Wallace ER, Starr JR, Cradock MM, Buono L, et al. Intellectual and academic functioning of school-age children with single-suture craniosynostosis. Pediatrics 2015;135(3):e615-623. [DOI:10.1542/peds.2014-1634] [PMID] [PMCID]
10. Speltz ML, Kapp-Simon KA, Cunningham M, Marsh J, Dawson G. Single-suture craniosynostosis: a review of neurobehavioral research and theory. J Pediatr Psychol 2004;29(8):651-668. [DOI:10.1093/jpepsy/jsh068] [PMID]
11. Tamburrini G, Caldarelli M, Massimi L, Santini P, Di Rocco C. Intracranial pressure monitoring in children with single suture and complex craniosynostosis: a review. Childs Nerv Syst 2005;21(10):913-921. [DOI:10.1007/s00381-004-1117-x] [PMID]
12. Costa ACD, Walters I, Savarirayan R, Anderson VA, Wrennall JA, Meara JG. Intellectual outcomes in children and adolescents with syndromic and nonsyndromic craniosynostosis. Plast Reconstr Surg 2006;118(1):175-181. [DOI:10.1097/01.prs.0000221009.93022.50] [PMID]
13. Becker DB, Petersen JD, Kane AA, Cradock MM, Pilgram TK, Marsh JL. Speech, cognitive, and behavioral outcomes in nonsyndromic craniosynostosis. Plast Reconstr Surg 2005;116(2):400-407. [DOI:10.1097/01.prs.0000172763.71043.b8] [PMID]
14. Chieffo D, Tamburrini G, Massimi L, Di Giovanni S, Giansanti C, Caldarelli M, et al. Long-term neuropsychological development in single-suture craniosynostosis treated early. J Neurosurg Pediatr 2010;5(3):232-237. [DOI:10.3171/2009.10.PEDS09231] [PMID]
15. Wechsler D. The Wechsler Preschool and Primary Scale of Intelligence, 3rd Edition (WPPSI-III). 2002. San Antonio, TX: The Psychological Corporation. [DOI:10.1037/t15177-000]
16. Wechsler D. Wechsler Intelligence Scale for Children, 4th Edition (WISC-IV). 2003. San Antonio, TX: The Psychological Corporation. [DOI:10.1037/t15174-000]
17. Gomez R, Vance A, Watson SD. Structure of the Wechsler Intelligence Scale for Children - Fourth
18. Edition in a Group of Children with ADHD. Front Psychol. 2016;7:737.
19. Williams PE, Weiss LG, Rolfhus EL. Psychometric Properties (WISC-IV Technical Report No.2). 2003. San Antonio. TX: Psychological Corp 9.
20. Kalantar-Hormozi A, Abbaszadeh-Kasbi A, Goravanchi F, Davai NR. Prevalence of Rare Craniofacial Clefts. J Craniofac Surg 2017;28(5):e467-e470. [DOI:10.1097/SCS.0000000000003771] [PMID]
21. Kalantar-Hormozi H, Abbaszadeh-Kasbi A, Sharifi G, Davai NR, Kalantar-Hormozi A. Incidence of Familial Craniosynostosis Among Patients with Nonsyndromic Craniosynostosis. J Craniofac Surg 2019. 30(6):e514-e517. [DOI:10.1097/SCS.0000000000005419] [PMID]
22. Lajeunie E, Crimmins DW, Arnaud E, Renier D. Genetic considerations in nonsyndromic midline craniosynostoses: a study of twins and their families. J Neurosurg 2005;103(4):353-356. [DOI:10.3171/ped.2005.103.4.0353] [PMID]
23. Cohen MM. Epidemiology of Craniosynostosis. In: Cohen MM Jr, MacLean RE, editors. Craniosynostosis: Diagnosis, Evaluation and Management. 2nd ed. New York: Oxford University Press; 2000. Pp:112-118.
24. Wallace ER, Collett BR, Kapp-Simon K, Starr JR, Birgfeld C, Speltz ML. Visuomotor Function in School-Age Children with Single-Suture Craniosynostosis. J Dev Behav Pediatr 2016;37(6):483-490. [DOI:10.1097/DBP.0000000000000319] [PMID] [PMCID]
25. Chieffo D, Ricci D, Baranello G, Martinelli D, Veredice C, Lettori D, et al. Early development in Dravet syndrome; visual function impairment precedes cognitive decline. Epilepsy Res 2011;93(1):73-79. [DOI:10.1016/j.eplepsyres.2010.10.015] [PMID]
26. Mendonca DA, White N, West E, Dover S, Solanki G, Nishikawa H. Is there a relationship between the severity of metopic synostosis and speech and language impairments? J Craniofac Surg 2009;20(1):85-88. [DOI:10.1097/SCS.0b013e3181955244] [PMID]
27. Shipster C, Hearst D, Somerville A, Stackhouse J, Hayward R, Wade A. Speech, language, and cognitive development in children with isolated sagittal synostosis. Dev Med Child Neurol 2003;45(1):34-43. https://doi.org/10.1017/S0012162203000070 [DOI:10.1111/j.1469-8749.2003.tb00857.x] [PMID]
28. Magge SN, Westerveld M, Pruzinsky T, Persing JA. Long-term neuropsychological effects of sagittal craniosynostosis on child development. J Craniofac Surg 2002;13(1):99-104. [DOI:10.1097/00001665-200201000-00023] [PMID]
29. Boltshauser E, Ludwig S, Dietrich F, Landolt MA. Sagittal craniosynostosis: cognitive development, behaviour, and quality of life in unoperated children. Neuropediatrics. 2003;34(6):293-300. [DOI:10.1055/s-2003-44667] [PMID]
30. Kelleher MO, Murray DJ, McGillivary A, Kamel MH, Allcutt D, Earley MJ. Behavioral, developmental, and educational problems in children with nonsyndromic trigonocephaly. J Neurosurg 2006;105(5):382-384. [DOI:10.3171/ped.2006.105.5.382] [PMID]
31. Osborn AJ, Roberts RM, Mathias JL, Anderson PJ, Flapper WJ. Cognitive, behavioral and psychological functioning in children with metopic synostosis: a meta-analysis examining the impact of surgical status. Child Neuropsychol 2019;25(2):263-277. [DOI:10.1080/09297049.2018.1441821] [PMID]
32. Kapp-Simon KA, Wallace E, Collett BR, Cradock MM, Crerand CE, Speltz ML. Language, learning, and memory in children with and without single-suture craniosynostosis. J Neurosurg Pediatr 2016;17(5):578-588. [DOI:10.3171/2015.9.PEDS15238] [PMID]
33. Bellew M, Chumas P. Long-term developmental follow-up in children with nonsyndromic craniosynostosis. J Neurosurg Pediatr 2015;16(4):445-451. [DOI:10.3171/2015.3.PEDS14567] [PMID]
34. Collett BR, Kapp-Simon KA, Wallace E, Cradock MM, Buono L, Speltz ML. Attention and executive function in children with and without single-suture craniosynostosis. Child Neuropsychol 2017;23(1):83-98. [DOI:10.1080/09297049.2015.1085005] [PMID] [PMCID]

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