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:: Volume 7, Issue 1 (1-2018) ::
wjps 2018, 7(1): 34-44 Back to browse issues page
Comparison of Albizia Julibressin and Silver Sulfadiazine in Healing of Second and Third Degree Burns
Hossein Asgarirad , Aroona Chabra , Mahnaz Rahimnejad , Ahmad Zaghi Hosseinzadeh , Ali Davoodi , Mohammad Azadbakht
Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
Abstract:   (731 Views)

BACKGROUND
Large numbers of population suffer from burn annually. The promising treatment of burn has not been identified yet. Albizia julibressin (A. julibressin) in Fabaceae family is popular for its antiseptic activity. This prospective study was designed to compare the wound healing effects of A. julibressin gel (AG) with silver sulfadiazine (SSD).
METHODS
This single blind clinical trial was performed on 40 patients with second and third degree burns. 20 patients treated with SSD and 20 other patients received A. julibressin. The percentage of the wound healing was evaluated with pain, irritation, edema, itching, erythema, purulent discharges and skin discoloration symptoms. Also, the patients’ satisfaction and adverse drug reactions were determined.
RESULTS
The severity of pain (p=0.03), inflammation (p=0.02) and purulent secretions (p=0.03) were significantly relieved in A. julibressin group. The healing time significantly reduced in second degree burns (p=0.03) and third degree burns (p=0.04) with treating by A. julibressin. No significant adverse drug reactions were detected with A. julibressin.
CONCLUSION
It seems that A. julibressin improves the different therapeutic aspects of burn injuries and could be considered as a new herbal remedy in wound healings.

Keywords: Herbal Medicine, Burns, Wound, Healing, Albizia julibressin
Full-Text [PDF 2010 kb]   (311 Downloads)    
Type of Study: Original Article | Subject: General
Received: 2017/07/4 | Accepted: 2017/11/4 | Published: 2017/12/23
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Asgarirad H, Chabra A, Rahimnejad M, Zaghi Hosseinzadeh A, Davoodi A, Azadbakht M. Comparison of Albizia Julibressin and Silver Sulfadiazine in Healing of Second and Third Degree Burns. wjps. 2018; 7 (1) :34-44
URL: http://wjps.ir/article-1-350-en.html


Volume 7, Issue 1 (1-2018) Back to browse issues page
مجله جهانی جراحی پلاستیک World Journal of Plastic Surgery
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