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:: Volume 4, Issue 1 (1-2015) ::
wjps 2015, 4(1): 23-28 Back to browse issues page
The Healing Effect of Nettle Extract on Second Degree Burn Wounds
Hosein Akbari , Mohammad Javad Fatemi , Maryam Iranpour , Ali Khodarahmi , Mehrdad Baghaee , Mir Sepehr Pedram , Sahar Saleh , Shirin Araghi
Abstract:   (4162 Views)
BACKGROUND Numerous studies were carried out to develop more sophisticated dressings to expedite healing processes and diminish the bacterial burden in burn wounds. This study assessed the healing effect of nettle extract on second degree burns wound in rats in comparison with silver sulfadiazine and vaseline. METHODS Forty rats were randomly assigned to four equal groups. A deep second-degree burn was created on the back of each rat using a standard burning procedure. The burns were dressed daily with nettle extract in group 1, silver sulfadiazine in group 2, vaseline in group 3 and without any medication in group 4 as control group. The response to treatment was assessed by digital photography during the treatment until day 42. Histological scoring was undertaken for scar tissue samples on days 10 and 42. RESULTS A statistically significant difference was observed in group 1 compared with other groups regarding 4 scoring parameters after 10 days. A statistically significant difference was seen for fibrosis parameter after 42 days. In terms of difference of wound surface area, maximal healing was noticed at the same time in nettle group and minimal repair in the control group. CONCLUSION Our findings showed maximal rate of healing in the nettle group. So it may be a suitable substitute for silver sulfadiazine and vaseline when available.
Keywords: Healing, Nettle, Burn, Wound, Silver sulfadiazine, Vaseline, Rat
Full-Text [PDF 1097 kb]   (2067 Downloads)    
Type of Study: Original Article | Subject: Special
Received: 2014/10/26 | Accepted: 2014/10/26 | Published: 2014/10/26
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Akbari H, Fatemi M J, Iranpour M, Khodarahmi A, Baghaee M, Pedram M S, et al . The Healing Effect of Nettle Extract on Second Degree Burn Wounds. wjps. 2015; 4 (1) :23-28
URL: http://wjps.ir/article-1-123-en.html

Volume 4, Issue 1 (1-2015) Back to browse issues page
مجله جهانی جراحی پلاستیک World Journal of Plastic Surgery
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