Showing 12 results for Fard
Mahmoud Omranifard, Hosein Abdali, Mehdi Rasti Ardakani, Amiryousef Ahmadnia,
Volume 2, Issue 2 (7-2013)
Abstract
BACKGROUND
Nasal valve collapse and especially internal nasal valve insufficiency is a common cause of nasal airway obstruction. This study compares the effects of spreader graft and overlapping lateral crural technique on rhinoplasty by rhinomanometry.
METHODS
Fifty patients were randomly assigned into two groups and underwent spreader graft or overlapping lateral crural technique. Objective assessment was performed by clinical examination and rhinomanometry before and after rhinoplasty.
RESULTS
Nasal obstruction had no significant difference before and after rhinoplasty and no significant difference was observed between surgical techniques. Right, left and total nasal flow and resistance were different before and after surgery but were not significant. Base of the nose was not significantly different between two groups, but nasal projection was 2 mm in the the group who underwent overlapping lateral crura technique and the difference was statistically significant. Our study showed that both overlapping lateral crura and spreader graft technique were beneficial in rhinoplasty and they could provide enough internal nasal valve support. The overlapping lateral crura was an appropriate surgical technique for tip projection in comparison to spreader graft.
CONCLUSION
The overlapping lateral crura technique was shown to be a better surgical way for tip projection in comparison to spreader graft.
Ebrahim Nasiri, Seyed Jalal Hosseinimehr, Mohammad Azadbakht, Jafar Akbari, Reza Enayati-Fard, Sohail Azizi, Masoud Azadbakht,
Volume 4, Issue 2 (7-2015)
Abstract
Background
Burn is still a majordevastating condition in emergency medicine departments among both genders and all age groups in all developed and developing countries, leading to physical, psychological scars and economical burden. The present study aimed to determine the healing effect of topical treatment with Arnebia euchroma on second-degree burn wound in rats.
Methods
Fifty rats were divided into 4 equal groups receiving the ointment base, normal saline (NS), standard 1% silver sulfadiazine (SSD), and 5% and 10% Arnebia euchroma ointments (AEO). The mean of burn area, percentage of wound contraction, histopathological and bacteriological assessments in the injured area were dtermined during the study.
Results
Average area of wound on the 10th day was 10.2±2.3, 8.4±2.6, 12.4±2.5, 5.9±2.2 and 5.7±2 cm2 for ointment base, NS, 1% SSD, and 5% and 10% AEO, respectively. Wound size was significantly lower in 10% AEO than 1% SSD and control groups on the 10th day post-burn injury. On day 11, the percentage of wound contraction in 5% and 10% AEO was 53.9%±14.7% and 55.9±10.5% which was more than 1% SSD (15.3±10.8%). The collagen fibers were well formed and horizontally-oriented in 5% and 10% AEO groups when compared with other groups.
Conclusion
Arnebia euchroma ointment was an effective treatment for healing of burn wounds in comparison with SSD and can be regarded as an alternative topical treatment for burn wounds.
Hossein Faramarzi, Davood Mehrabani, Maryam Fard, Maryam Akhavan, Sona Zare, Shabnam Bakhshalizadeh, Amir Manafi, Somaieh Kazemnejad, Reza Shirazi,
Volume 5, Issue 1 (1-2016)
Abstract
BACKGROUND Menstrual blood-derived stem cells (MenSCs) are a novel source of stem cells that can be easily isolated non-invasively from female volunteered donor without ethical consideration. These mesenchymal-like stem cells have high rate of proliferation and possess multi lineage differentiation potency. This study was undertaken to isolate the MenSCs and assess their potential in differentiation into epidermal lineage. METHODS About 5-10 ml of menstrual blood (MB) was collected using sterile Diva cups inserted into vagina during menstruation from volunteered healthy fertile women aged between 22-30 years. MB was transferred into Falcon tubes containing phosphate buffered saline (PBS) without Ca2+ or Mg2+ supplemented with 2.5 µg/ml fungizone, 100 µg/mL streptomycin, 100 U/mL penicillin and 0.5 mM EDTA. Mononuclear cells were separated using Ficoll-Hypaque density gradient centrifugation and washed out in PBS. The cell pellet was suspended in DMEM-F12 medium supplemented with 10% FBS and cultured in tissue culture plates. The isolated cells were co-cultured with keratinocytes derived from the foreskin of healthy newborn male aged 2-10 months who was a candidate for circumcision for differentiation into epidermal lineage. RESULTS The isolated MenSCs were adhered to the plate and exhibited spindle-shaped morphology. Flow cytometric analysis revealed the expression of mesenchymal markers of CD10, CD29, CD73, and CD105 and lack of hematopoietic stem cells markers. An early success in derivation of epidermal lineage from MenSCs was visible. CONCLUSION The MenSCs are a real source to design differentiation to epidermal cells that can be used non-invasively in various dermatological lesions and diseases.
Davood Mehrabani, Fereidoon Mojtahed Jaberi, Maryam Zakerinia, Mohammad Javad Hadianfard, Reza Jalli, Nader Tanideh, Shahrokh Zare,
Volume 5, Issue 2 (4-2016)
Abstract
Osteoarthritis (OA) is a prevalent chronic disease impacting on quality of life and has societal and economical burden increasing with age. Yet, no confirmed pharmacological, biological or surgical therapy could prevent the progressive destruction of OA joint. Mesenchymal stem cells (MSCs) with immunosuppressive activities emerged a potential therapy. We describe a magnetic resonance images (MRI) approved 47 years old nomad female suffering from a severe right knee OA. After intra-articular injection of 36×106 passage 2 of bone marrow-derived stem cells (BMSCs), the patient’s functional status of the knee, the number of stairs she could climb, the pain on visual analog scale (VAS) and walking distance improved after two months post-transplantation. MRI revealed an extension of the repaired tissue over subchondral bone. So as MSC transplantation is a simple technique, resulted into pain relief, minimized donor-site morbidity, provided a better quality of life, significantly improved cartilage quality with no need to hospitalization or surgery, cell transplantation can be considered as a reliable alternative treatment for chronic knee OA. Therefore these findings can be added to the literature on using BMSCs for treatment of OA.
Fatemeh Hosseinzadeh, Moosa Salehi, Nader Tanideh, Davood Mehrabani, Azadeh Sayarifard, Anahita Sedighi,
Volume 6, Issue 2 (4-2017)
Abstract
BACKGROUND
Inflammatory bowel diseases contain two digestive system diseases, ulcerative colitis (UC) and Crohn’s disease with unclear causes. The aim of present study was to investigate the therapeutic effects of administration of the Sesame oil (SO) and grape seed oil (GSO) as enema route in rats suffering from experimental acetic acid induced UC.
METHODS
Eighty male rats were randomly allocated into 8 equal groups as health control (HC1) without any disease treated with 1 ml of normal saline as enema; HC2 received SO; HC3 received GSO; negative control (NC) with induced UC receiving 1 ml of normal saline as enema; and positive control (PC) with induced UC treated by asacol. All treatments were performed identically with 4 mg/kg of medication except for asacol that was 100 mg/kg for 7 days. The weight changes was recorded after seven days. The serum levels of malondialdehyde (MDA), total antioxidant capacity (TAC), interleukin-6, and c-reactive protein (CRP) were measured. Colon macroscopic and microscopic histological changes were also measured at the end of 7th day.
RESULTS
No significant changes were detected in weight in neither groups on day 0 nor at the end of study. No beneficial effects were seen for all treatments regarding healing process and the decrease in inflammation. Between treatment groups, the lowest MDA (7.40±0.98 U/ml), CRP (83.20±10.01 mg/l) and IL-6 levels (130.86±10.70 mU/ml) and highest TAC (1.91±0.43 mmol/l) belonged to GSO group.
CONCLUSION
GSO enema alone can be considered as a treatment of choice for UC due to its antioxidant properties
Abolfazl Afsharfard, Mohammad Bashir Khodaparast, Sina Zarrintan, Negin Yavari,
Volume 9, Issue 1 (1-2020)
Abstract
BACKGROUND
Hidradenitis suppurativa is a chronic inflammatory disease with multiple inflammatory nodules and abscesses. We aimed to compare split thickness skin graft (STSG) and flaps in bilateral chronic refractory axillary hidradenitis suppurativa.
METHODS
Thirty patients were investigated from March 21, 2010 to March 20, 2015. Debridement of involved skin and subcutaneous fat was done until deep fascia. The second operation was a reconstructive procedure to cover bilateral axillary wounds with STSG in left side and random fasciocutaneous flaps in the right side.
RESULTS
Mean age of patients was 35.2±9.3 years. There were 16 men (53.3%) and 14 women (46.7%). Duration of the disease before trial was 6.5±2.1 years. The association between pain at one-month follow-up for graft or flap sites was not significant. The patients did not have pain at flap and graft sites at three-month, six-month and one-year follow-ups. Twenty-four patients (80.0%) had normal ranges of motion at one-month follow-up. At six-month and one-year follow-ups, all patients had bilateral normal ranges of motion. All patients were satisfied from symmetry of flap and graft sites at six-month and one-year follow-ups. All patients were satisfied from graft and flap donor sites at six-month and one-year follow-ups. At one-month, three-month, six-month and one-year follow-ups, recurrence of hidradenitis suppurativa was not seen.
CONCLUSION
Both STSGs and fasciocutaneous flaps were successful and satisfactory for tissue coverage in patients with axillary hidradenitis suppurativa. We recommend this technique in cases of bilateral axillary hidradenitis suppurativa.
Ladan Esmalian Khamseh, Mahmood Nodargahfard,
Volume 9, Issue 2 (4-2020)
Abstract
BACKGROUND
Nowadays in different communities, we are confronting an ever-increasing trend of cosmetic surgeries. The present research was carried out with the aim of investigating sexual self-esteem, attitude to body image and well-being in married women aged from 20 to 30 years old before and after cosmetic surgery in Tehran, Iran.
METHODS
The research was a semi-experimental design with pre- and post-test. The statistical population consisted 80 married women. The research sample was selected by means of the convenience sampling approach. This group was similar in terms of age, education, and marital status. The research data were accumulated using the Zeanah and Schwarz sexual self-esteem questionnaire, the Fisher body image questionnaire and the Ryff psychological well-being questionnaire, and were analyzed by multivariate analysis of variance.
Results
The average scores of all three variables, involving "sexual self-esteem", "body image" and "well-being" were dramatically different before and after cosmetic surgery (p<0.05).
Conclusion
It can be ascertained that people after cosmetic surgery had higher sexual self-esteem, were more satisfied with their body image, and experienced more well-being.
Mahmood Omranifard, Mehdi Rasti Ardakani, Hossein Abdali, Pejman Mortazavi, Saeed Hoseini, Mohammad Ali Hoghoughi,
Volume 10, Issue 2 (2-2021)
Abstract
BACKGROUND
Given the potential usefulness of Acellular Dermal Matrices (ADM) for wound healing, we aimed to evaluate the stability, histological characteristics, and effectiveness of ADM compared with cryopreserved dermis (CPD) in rat models.
METHODS
This experimental study was conducted in the Department of Surgery, Isfahan University of Medical Sciences, Isfahan, Iran, from January to March 2015. The prepared ADM and CPD were transplanted to the full-thickness skin defects on the back of Sprague-Dawley rats. Forty-five days after grafting, the tissues were harvested for histological examination. These two types of the dermis' quality and stability were compared with consideration of the following factors; inflammation, fibroblasts migration, vascularization, collagen formation, capsule formation, and microabscess formation.
RESULTS
From 19 selected rates, nine received CPD, and ten were treated with ADM. After transplantation, the mean (SD) weight of ADM and CPD grafts were 1.74 (0.07) and 1.45 (0.77), respectively (P<0.001). The frequency of inflammation was significantly higher in CPD grafts (P<0.01). Higher grades of collagen organization, fibroblast spreading, and vascularization were more frequent in ADM grafts (P<0.01). The frequency of capsule and microabscesses formation was not significantly different between studied groups.
CONCLUSION
ADM have a superior effect than CPD in the wound healing process. Both samples had a similar effect in capsule and microabscesses formation and higher costs of ADM preparation. According to the physicians' decision and evaluation of the process's cost-effectiveness, CPD could be appropriately used as an alternative to ADM.
Mohammad Bahadoram, Amar Helalinasab, Najmeh Namehgoshay-Fard, Esma’il Akade, Roozbeh Moghaddar,
Volume 12, Issue 1 (2-2023)
Abstract
Platelet-rich plasma (PRP) is part of the blood with a high concentration of platelets. The history of PRP application began in the field of hematology. However, it spread to other areas of medicine as well. In this essay, we briefly highlight the current applications of PRP in plastic surgery
Mohammad Bahadoram, Gholamreza Shamsaei, Mohammad Sharifi Fard, Esma’il Akade, Shayan Davoodi,
Volume 12, Issue 2 (5-2023)
Abstract
Homa Farhadifard, Abbas Shokri, Maryam Salehzadeh , Maryam Farhadian , Yousef Ahmadpour,
Volume 13, Issue 2 (5-2024)
Abstract
Background: We aimed to evaluate the morphology of maxilla and sinus dimension in subjects with unilaterally and bilaterally impacted canine using cone beam computed tomography (CBCT) records.
Methods: CBCT records taken during 2020-2022 of 120 patients were obtained to investigate the relationship between impacted canine and maxilla morphology as well as sinus dimension. The CBCT images were then divided into three control, unilaterally and bilaterally canine impaction groups. Then morphology-related variables (arch circumference and arch length , inter molar width, inter first molar width, palatal depth, anterior posterior of right and left side sinus, and mediolateral dimension of right and left side sinus) were analyzed and compared between groups. All measurements was measured by Ondeman3D dental software, the unit of measurement was millimeter. Statistical analysis was carried out by SPSS software version 21 using one-way ANOVA and post hoc tests.
Results: In patients with canine impaction (compared with control group), there were meaningful differences in arch circumference (P value= 0.004) and arch length (P value= 0.001), inter molar width (P value= 0.001), inter first premolar width (P value= 0.001), mediolateral dimension of right (P value=0.001) and left side (P value= 0.001) sinus of maxilla. Furthermore, Palatal depth and anterior posterior of right and left sinuses were not statistically significant difference between groups.
Conclusion: Canine impaction can considerably affect the morphology of maxillary and sinuses dimension. Nevertheless, future studies are needed to determine the exact structural and molecular effects that canine impaction can have on maxillary sinuses and neighboring tissues.
Abolfazl Afsharfard, Hamed Ebrahimibagha, Armin Mohammadi, Adel Zeinalpour,
Volume 13, Issue 3 (11-2024)
Abstract
Background: Breast-conserving surgery (BCS) and post-surgical radiotherapy are the treatment of choice in early-stage breast cancers. Surgeons use different techniques for the reconstruction of the breast after BCS. We aimed to present our novel reconstruction technique for medial breast defects and report the follow-up results of patients who underwent breast reconstruction using this method in the short and long term.
Methods: Forty patients with medially located breast tumors under BCS referred to Shahid Modares Hospital in Tehran, Iran from 2018 to 2022 were enrolled in the study. The patients underwent breast reconstruction post-lumpectomy using the local transposition flap technique. We followed the patients for one year, and the satisfaction and complication results were assessed and reported post-operation, after radio-chemotherapy, and after one year.
Results: The patients’ mean age was 48.4 (±12.3) years, and the mean BMI was 30.9 (±3.1). There were no cases of complication, including infection, seroma formation, hematoma, flap ischemia, or necrosis post-operation, one week and one month after discharge. The surgeon and patient satisfaction surveys conducted post-op, after the radio-chemotherapy course, and one year after BCS using the Breast-Q satisfaction domain showed that the excellent and good satisfaction rates are 88%, 92%, and 92%, respectively.
Conclusion: Local transposition flap has remarkable cosmetic results with the least complication rate in the reconstruction of medial breast defects after breast-conserving surgery and is an excellent choice for surgeons.
