WORLD JOURNAL OF PLASTIC SURGERY
Fri, Aug 29, 2025
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Volume 14, Issue 2 (2025)
WJPS 2025, 14(2): 72-78 |
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Kazemian N, Khorami M, Grillo R, Hashemzadeh H, Bardideh E, Family K, et al . COVID-19 Influence on Mandibular Dry Socket Occurrence. WJPS 2025; 14 (2) :72-78
URL: http://wjps.ir/article-1-1471-en.html
URL: http://wjps.ir/article-1-1471-en.html
Navid Kazemian1 
, Mozhgan Khorami1 , Ricardo Grillo2 , Haleh Hashemzadeh3 , Erfan Bardideh4 , Khashayar Family5 , Alireza Ebrahimpour1 , Sahand Samieirad *6
, Mozhgan Khorami1 , Ricardo Grillo2 , Haleh Hashemzadeh3 , Erfan Bardideh4 , Khashayar Family5 , Alireza Ebrahimpour1 , Sahand Samieirad *6
1- Student Research Committee, Mashhad Dental School, Mashhad University of Medical Sciences, Mashhad, Iran
2- Department of Oral and Maxillofacial Surgery, University of São Paulo, São Paulo, Brazil
3- orthodontist, Tehran University of Medical Sciences, Tehran, Iran
4- Department of Oral and Maxillofacial Surgery, Mashhad Dental School, Mashhad University of Medical Sciences, Mashhad, Iran
5- Dental Research Center, Mashhad Dental School, Mashhad University of Medical Sciences, Mashhad, Iran
6- Department of Oral and Maxillofacial Surgery, Mashhad Dental School, Mashhad University of Medical Sciences, Mashhad, Iran ,SamieeRadS@mums.ac.ir
2- Department of Oral and Maxillofacial Surgery, University of São Paulo, São Paulo, Brazil
3- orthodontist, Tehran University of Medical Sciences, Tehran, Iran
4- Department of Oral and Maxillofacial Surgery, Mashhad Dental School, Mashhad University of Medical Sciences, Mashhad, Iran
5- Dental Research Center, Mashhad Dental School, Mashhad University of Medical Sciences, Mashhad, Iran
6- Department of Oral and Maxillofacial Surgery, Mashhad Dental School, Mashhad University of Medical Sciences, Mashhad, Iran ,
Abstract: (423 Views)
Background: Alveolar osteitis (AO), commonly known as dry socket, is a recognized complication following tooth extraction, particularly prevalent after mandibular third molar extractions. Given the global pandemic of coronavirus disease (COVID-19) and its implications for endothelial and hematologic changes, investigating its potential impact on dry socket risk in patients undergoing mandibular third molar extraction is crucial.
Methods: We reviewed patient records from individuals undergoing mandibular third molar extraction at Mashhad Dental School, Mashhad, Iran in 2022. Data included demographics, medical history, smoking status, and COVID-19 details such as history, hospitalization, and vaccination status.
Results: Clinical examinations diagnosed alveolar osteitis, assessing for blood clot presence and local lymphadenitis. Out of 119 patients (82 females, 37 males), 49.6% developed dry socket post-extraction, with 94.1% having a history of COVID-19 and 32.7% requiring hospitalization due to the disease. 97.5% of patients were vaccinated against COVID-19. Additionally, 44.5% had systemic disease history, and 45.4% used related medications, with no observed associations with dry socket.
Conclusion: This study underscores the increased risk of dry socket following mandibular third molar extraction associated with corticosteroid use, oral contraceptive use, smoking, and COVID-19 hospitalization. Females exhibited a significantly higher risk compared to males. While no significant COVID-19 infection-dry socket link was found, the study highlights the need for further research, given the significant number of dry socket cases among COVID-19 patients and those hospitalized due to COVID-19.
Methods: We reviewed patient records from individuals undergoing mandibular third molar extraction at Mashhad Dental School, Mashhad, Iran in 2022. Data included demographics, medical history, smoking status, and COVID-19 details such as history, hospitalization, and vaccination status.
Results: Clinical examinations diagnosed alveolar osteitis, assessing for blood clot presence and local lymphadenitis. Out of 119 patients (82 females, 37 males), 49.6% developed dry socket post-extraction, with 94.1% having a history of COVID-19 and 32.7% requiring hospitalization due to the disease. 97.5% of patients were vaccinated against COVID-19. Additionally, 44.5% had systemic disease history, and 45.4% used related medications, with no observed associations with dry socket.
Conclusion: This study underscores the increased risk of dry socket following mandibular third molar extraction associated with corticosteroid use, oral contraceptive use, smoking, and COVID-19 hospitalization. Females exhibited a significantly higher risk compared to males. While no significant COVID-19 infection-dry socket link was found, the study highlights the need for further research, given the significant number of dry socket cases among COVID-19 patients and those hospitalized due to COVID-19.
Keywords: COVID-19, Dry Socket, Surgery, Surgery, Oral Surgery, Postoperative Complications, Osteitis
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