WORLD JOURNAL OF PLASTIC SURGERY
Wed, Aug 27, 2025
[Archive]
Alaa Hakami *1 
, Alya Hakami2 , Rayan Alghamdi , Haya Alzahrani3 , Adham Alghamdi3 , Abdullah Qureshey4 , Yousef Almail5 , Manar Alfaqiri6 , Maha Alsofiani7 , Lana Hariri8 , Hajar Alrashed9 , Shahad Aldumkh10
, Alya Hakami2 , Rayan Alghamdi , Haya Alzahrani3 , Adham Alghamdi3 , Abdullah Qureshey4 , Yousef Almail5 , Manar Alfaqiri6 , Maha Alsofiani7 , Lana Hariri8 , Hajar Alrashed9 , Shahad Aldumkh10
1- 1. Department of Surgery, Jazan University Jazan, Saudi Arabia , alaahakami@jazanu.edu.sa
2- 1. Department of Surgery, Jazan University Jazan, Saudi Arabia
3- 3. Department of Surgery, Al-Baha University, Saudi Arabia
4- 4. Department of Surgery, University of Jeddah, Jeddah, Saudi Arabia
5- 5. Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland
6- 6. Department of Surgery, University of Tabuk, Tabuk, Saudi Arabia
7- 7. Department of Surgery, Taif university, Taif, Saudi Arabia
8- 8. Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia
9- 9. Department of Surgery, Princesses Nourah University, Riyadh, Saudi Arabia
10- 10. Department of Surgery, King Saud University, Riyadh, Saudi Arabia
2- 1. Department of Surgery, Jazan University Jazan, Saudi Arabia
3- 3. Department of Surgery, Al-Baha University, Saudi Arabia
4- 4. Department of Surgery, University of Jeddah, Jeddah, Saudi Arabia
5- 5. Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland
6- 6. Department of Surgery, University of Tabuk, Tabuk, Saudi Arabia
7- 7. Department of Surgery, Taif university, Taif, Saudi Arabia
8- 8. Department of Surgery, King Abdulaziz University, Jeddah, Saudi Arabia
9- 9. Department of Surgery, Princesses Nourah University, Riyadh, Saudi Arabia
10- 10. Department of Surgery, King Saud University, Riyadh, Saudi Arabia
Abstract: (38 Views)
Background: Cryolipolysis has emerged as a promising, non-invasive body contouring technique that employs controlled cooling to selectively eliminate adipocytes without damaging surrounding skin or tissues. As global demand rises for non-surgical aesthetic treatments, cryolipolysis offers an appealing alternative to traditional liposuction for individuals seeking fat reduction with minimal recovery time and fewer complications.
Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a comprehensive search of PubMed, Scopus, and Web of Science was conducted up to November 2024. Studies included were randomized controlled trials and prospective cohort studies evaluating the outcomes of cryolipolysis on body contouring. Statistical analysis was performed using Review Manager 5.4 software, calculating mean differences (MD) and 95% confidence intervals (CI).
Results: The use of cryolipolysis was associated with decreased BMI showing MD= -1.71 (95%CI: -2.6, -0.82, P=0.0002). However, no significant difference was observed regarding weight with MD= -1.81 (95%CI: -3.93, 0.31, P=0.09). The use of cryolipolysis was also associated with decreased circumference of different body parts with MD= -3.45 (95%CI: -5.55, -1.34, P=0.001), and I2=92%, P<0.00001 and decreased fat thickness with MD= -3.56 (95CI: -4.63, -2.48, P<0.00001), and I2=95%, P<0.00001.
Conclusion: Cryolipolysis is effective in reducing BMI, local circumference, and fat thickness, confirming its utility for non-invasive body contouring. However, it does not significantly affect overall weight. The benefits are more pronounced in short-term follow-up and vary by body region. Further long-term and comparative studies are recommended.
Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a comprehensive search of PubMed, Scopus, and Web of Science was conducted up to November 2024. Studies included were randomized controlled trials and prospective cohort studies evaluating the outcomes of cryolipolysis on body contouring. Statistical analysis was performed using Review Manager 5.4 software, calculating mean differences (MD) and 95% confidence intervals (CI).
Results: The use of cryolipolysis was associated with decreased BMI showing MD= -1.71 (95%CI: -2.6, -0.82, P=0.0002). However, no significant difference was observed regarding weight with MD= -1.81 (95%CI: -3.93, 0.31, P=0.09). The use of cryolipolysis was also associated with decreased circumference of different body parts with MD= -3.45 (95%CI: -5.55, -1.34, P=0.001), and I2=92%, P<0.00001 and decreased fat thickness with MD= -3.56 (95CI: -4.63, -2.48, P<0.00001), and I2=95%, P<0.00001.
Conclusion: Cryolipolysis is effective in reducing BMI, local circumference, and fat thickness, confirming its utility for non-invasive body contouring. However, it does not significantly affect overall weight. The benefits are more pronounced in short-term follow-up and vary by body region. Further long-term and comparative studies are recommended.
Keywords: Cryolipolysis, Body Contouring, Non-Invasive Fat Reduction, BMI, Circumference, Fat Thickness
Type of Study: Review Article |
Subject:
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