[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: ::
Back to the articles list Back to browse issues page
The Effect of Mentha Pulegium on Healing of Burn Wound Injuries in Rat
Reza Vaghardoost , Yaser Ghavami , Behnam Sobouti
Abstract:   (163 Views)
Burn is one of the most common injuries and the 4th common cause of trauma globally. This study was designed to evaluate the effect of the Mentha pulegium extract on second degree burn injuries in rats assessing histopathologic and macroscopic.
M. Pulegium extract dressings was used as a treatment to deep dermal contact burns in rats, compared with two control groups of vaseline dressing and simple dressing by normal saline. After creating second-degree burn on the dorsum of rats, the treatments were applied for 15 min in three groups. Wound dressings were performed on days 1, 3, 7, 14 and 21st and at the same time macroscopic assessment was performed using a digital camera and software processing of photos. Pathologic evaluation of skin specimens was undertaken on days 1, 3,7, 14 and 21st. Wound healing parameters such as epithelialization, angiogenesis, granulation tissue formation, inflammatory cells were compared between these 3 groups.
Application of M. Pulegium extract on second degree burn wounds significantly decreased burn surface area and increased fibroblasts in comparison to simple dressing. There was not any statistically significant relationship between M. Pulegium extract treated group and vaseline treated or simple dressing groups on other wound healing parameters.  
This study delineated that M. Pulegium extract had a positive effect on healing process of second degree burns. 
Keywords: Mentha pulegium, Burn, Wound, Healing, Rat
Full-Text [PDF 1748 kb]   (59 Downloads)    
Type of Study: Original Article | Subject: General
Received: 2018/03/14
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Back to the articles list Back to browse issues page
مجله جهانی جراحی پلاستیک World Journal of Plastic Surgery
Persian site map - English site map - Created in 0.05 seconds with 32 queries by YEKTAWEB 3844