Volume 9, Issue 2 (4-2020)                   wjps 2020, 9(2): 128-134 | Back to browse issues page

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Rostami K, Shahaboddin M A, Niazi F, Karimi Rouzbahani A, Nadri S, Mahmoudvand H. The Effect of Hirodoid Cream on Ecchymosis and Edema around Eyes after Rhinoplasty. wjps. 2020; 9 (2) :128-134
URL: http://wjps.ir/article-1-607-en.html
Department of Surgery, Lorestan University of Medical Sciences, Khorramabad, Iran
Abstract:   (876 Views)
Several methods have been used to decrease the periorbital edema and ecchymosis after rhinoplasty. In this study, we evaluated the efficacy of hirudoid and dexamethasone in reduction of the periorbital edema and ecchymosis.
Sixty patients who underwent primary rhinoplasty were randomly divided into 3 groups. Group H received hirudoid cream, 3 times per day for 5 days from postoperative-day (POD). Group D received 10 mg of dexamethasone IV, immediately before surgery; and group C (control) received neither dexamethasone nor hirudoid. Two surgeons who were unaware of administered medications rated the severity of edema and intensity of ecchymosis, on 2nd, 5th, and 7th POD.
On 2nd POD, the edema in group D was significantly lower than groups H and C; but there was no significant difference in severity and intensity of ecchymosis between 3 groups. On 7th POD, the intensity of ecchymosis was significantly lower in group H in comparison to group C. When the difference between 2nd and 7th POD was evaluated, the resolution of severity of edema and intensity of ecchymosis was significantly better in group H (p<0.001).
Hirudoid was shown to be effective in reducing edema and ecchymosis after rhinoplasty. The use of dexamethasone was effective in prevention of periorbital edema at early postoperative days, but it was not effective on resolution of ecchymosis.
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Type of Study: Original Article | Subject: General
Received: 2020/03/16 | Accepted: 2020/04/13 | Published: 2020/04/13

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