WORLD JOURNAL OF PLASTIC SURGERY
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Volume 11, Issue 2 (2022)
WJPS 2022, 11(2): 62-67 |
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Tabassi K T, Mottaghi M, Nekooei N, Salehi S, Aghaee A, Soltani S. Saphenous Vein Graft for Treatment of Peyronie’s Disease, a Comparison between Single and Multiple Graft Reconstruction. WJPS 2022; 11 (2) :62-67
URL: http://wjps.ir/article-1-932-en.html
URL: http://wjps.ir/article-1-932-en.html
Kamyar Tavakoli Tabassi 
1, Mahdi Mottaghi2 , Negar Nekooei3 , Sanaz Salehi2 , Atena Aghaee4 , Salman Soltani4
1, Mahdi Mottaghi2 , Negar Nekooei3 , Sanaz Salehi2 , Atena Aghaee4 , Salman Soltani4
1- Department of Urology and Renal Transplantation, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
2- 2- Kidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
3- 3- Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4- Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2- 2- Kidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
3- 3- Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4- Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract: (1627 Views)
Background: Surgical reconstruction is the gold standard of treatment for Peyronie’s disease (PD). Grafting procedures provide satisfactory outcomes in patients with complex curvature, short penile length, and without previous erectile dysfunction (ED). We aimed to compare two different grafting methods of reconstruction in patients with PD.
Method: Fifty-two PD patients at Imam-Reza hospital of Mashhad from October 2011 to January 2019 with stable plaque, penile angulation of >60˚, complex curvature, and without ED who consented to cooperate, included in our study and divided into two groups. The first group consists of 26 patients, undergone grafting through a double-Y incision and a single saphenous graft placed within the incision. For the second group, two smaller saphenous vein grafts were placed in the two parallel incisions. ED assessed pre- and post-operational via the International index of erectile function. Penile angulation less than 20 degrees was considered a favorable outcome. Patients followed for 18 months, and sacculation, penile shortening, post-operation infection, and penile hypoesthesia were assessed as complications. We used a paired t-test to compare these two groups.
Results: ED was 25% and 12% in the first and the second group, respectively. Statistics showed no difference between the two groups regarding pre and post-operational ED (P=0.1). Regarding complications during follow-up, sacculation occurred in four patients of the first group and none of the second group patients but no significant difference (P=0.23).
Conclusion: We found no superiority to declare between these two procedures, although regarding the small sample size of our study, further evaluations are needed to establish more reliable results.
Method: Fifty-two PD patients at Imam-Reza hospital of Mashhad from October 2011 to January 2019 with stable plaque, penile angulation of >60˚, complex curvature, and without ED who consented to cooperate, included in our study and divided into two groups. The first group consists of 26 patients, undergone grafting through a double-Y incision and a single saphenous graft placed within the incision. For the second group, two smaller saphenous vein grafts were placed in the two parallel incisions. ED assessed pre- and post-operational via the International index of erectile function. Penile angulation less than 20 degrees was considered a favorable outcome. Patients followed for 18 months, and sacculation, penile shortening, post-operation infection, and penile hypoesthesia were assessed as complications. We used a paired t-test to compare these two groups.
Results: ED was 25% and 12% in the first and the second group, respectively. Statistics showed no difference between the two groups regarding pre and post-operational ED (P=0.1). Regarding complications during follow-up, sacculation occurred in four patients of the first group and none of the second group patients but no significant difference (P=0.23).
Conclusion: We found no superiority to declare between these two procedures, although regarding the small sample size of our study, further evaluations are needed to establish more reliable results.
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