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wjps 2017, 6(1): 94-99 Back to browse issues page
Can Skin Allograft Occasionally Act as a Permanent Coverage in Deep Burns? A Pilot Study
Ezzatollah Rezaei , Arash Beiraghi-Toosi , Ali Ahmadabadi , Seyed Hassan Tavousi , Arash Alipour Tabrizi , Kazem Fotuhi , Mehdi Jabbari Nooghabi , Amir Manafi , Shokoofeh Ahmadi Moghadam
Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:   (2622 Views)

Skin allograft is the gold standard of wound coverage in patients with extensive burns; however, it is considered as a temporary wound coverage and rejection of the skin allograft is considered inevitable. In our study, skin allograft as a permanent coverage in deep burns is evaluated.
Skin allograft survival was assessed in 38 patients from March 2009 to March 2014, retrospectively. Because of the lack of tissue specimen from the skin donors, patients with long skin allograft survival in whom the gender of donor and recipient of allograft was the same were excluded. Seven cases with skin allograft longevity and opposite gender in donor and recipient were finally enrolled. A polymerase chain reaction (PCR) test on the biopsy specimen from recipients and donors were undertaken.
PCR on the biopsy specimen from recipients confirmed those specimens belong to the donors. All patients received allograft from the opposite sex. Two (28.57%) patients received allograft from their first-degree blood relatives, and in one (14.29%) case, the allograft was harvested from an alive individual with no blood relation. The rest were harvested from multiorgan donors. In eight months of follow up, no clinical evidence of graft rejection was noted.
Long term persistence of skin allograft in patients is worthy of more attention. Further studies An increase in knowledge of factors influencing this longevity could realize the dream of burn surgeons to achieve a permanent coverage other than autograft for major burn patients.

Keywords: Skin allograft, Burn, Polymerase chain reaction
Full-Text [PDF 867 kb]   (1053 Downloads)    
Type of Study: Short Communication | Subject: Special
Received: 2016/02/1 | Accepted: 2016/12/21 | Published: 2016/12/21
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Rezaei E, Beiraghi-Toosi A, Ahmadabadi A, Tavousi S H, Alipour Tabrizi A, Fotuhi K, et al . Can Skin Allograft Occasionally Act as a Permanent Coverage in Deep Burns? A Pilot Study . wjps. 2017; 6 (1) :94-99
URL: http://wjps.ir/article-1-223-en.html

Volume 6, Issue 1 (1-2017) Back to browse issues page
مجله جهانی جراحی پلاستیک World Journal of Plastic Surgery
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